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ME2 malic enzyme 2 [ Ochotona princeps (American pika) ]

Gene ID: 101526216, updated on 8-Mar-2024

Summary

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Gene symbol
ME2
Gene description
malic enzyme 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Ochotona princeps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Ochotonidae; Ochotona
Orthologs
human mouse all
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Genomic context

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See ME2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_07 current mOchPri1.hap1 (GCF_030435755.1) 18 NC_080849.1 (18756923..18801351, complement)
102 previous assembly OchPri4.0 (GCF_014633375.1) 9 NC_050544.1 (19731775..19764221, complement)

Chromosome 18 - NC_080849.1Genomic Context describing neighboring genes Neighboring gene SMAD family member 4 Neighboring gene elaC ribonuclease Z 1 Neighboring gene large ribosomal subunit protein eL43-like Neighboring gene uncharacterized LOC131482503 Neighboring gene maestro

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables malate dehydrogenase (decarboxylating) (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables malate dehydrogenase (decarboxylating) (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in malate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pyruvate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NAD-dependent malic enzyme, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030435755.1-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOchPri1.hap1

Genomic

  1. NC_080849.1 Reference mOchPri1.hap1

    Range
    18756923..18801351 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004579493.4 → XP_004579550.1  NAD-dependent malic enzyme, mitochondrial

    Conserved Domains (3) summary
    cd05312
    Location:280 → 558
    NAD_bind_1_malic_enz; NAD(P) binding domain of malic enzyme (ME), subgroup 1
    PLN03129
    Location:28 → 566
    PLN03129; NADP-dependent malic enzyme; Provisional
    pfam00390
    Location:89 → 270
    malic; Malic enzyme, N-terminal domain
Nucleotide Protein
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Gene LinkOut

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