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mkrn1 makorin, ring finger protein, 1 [ Maylandia zebra (zebra mbuna) ]

Gene ID: 101475566, updated on 8-Mar-2024

Summary

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Gene symbol
mkrn1
Gene description
makorin, ring finger protein, 1
See related
Ensembl:ENSMZEG00005019125
Gene type
protein coding
RefSeq status
MODEL
Organism
Maylandia zebra
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex
Orthologs
human zebrafish all
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Genomic context

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See mkrn1 in Genome Data Viewer
Location:
chromosome: LG17
Exon count:
8
Annotation release Status Assembly LG Location
104 current M_zebra_UMD2a (GCF_000238955.4) LG17 NC_036796.1 (34924276..34939665)
101 previous assembly MetZeb1.1 (GCF_000238955.1) Unplaced Scaffold NW_004531746.1 (53109..69176, complement)

Linkage Group LG17 - NC_036796.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 178B Neighboring gene toll-like receptor 1 Neighboring gene transmembrane protein 121B Neighboring gene interleukin 17 receptor A1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase makorin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Maylandia zebra Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference M_zebra_UMD2a Primary Assembly

Genomic

  1. NC_036796.1 Reference M_zebra_UMD2a Primary Assembly

    Range
    34924276..34939665
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004553740.5 → XP_004553797.1  E3 ubiquitin-protein ligase makorin-1

    See identical proteins and their annotated locations for XP_004553797.1

    UniProtKB/TrEMBL
    A0A3P9CU73
    Related
    ENSMZEP00005025614.1, ENSMZET00005026448.1
    Conserved Domains (6) summary
    PHA03096
    Location:168 → 317
    PHA03096; p28-like protein; Provisional
    PHA03247
    Location:82 → 140
    PHA03247; large tegument protein UL36; Provisional
    COG5084
    Location:21 → 108
    YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]
    cd16730
    Location:225 → 285
    RING-HC_MKRN1_3; RING finger, HC subclass, found in makorin-1 (MKRN1), makorin-3 (MKRN3), and similar proteins
    pfam15815
    Location:339 → 431
    MKRN1_C; E3 ubiquitin-protein ligase makorin-1, C-terminal
    cl39030
    Location:315 → 337
    zf_CCCH_4; Zinc finger domain
Nucleotide Protein
Heading Accession and Version

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