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capn3b calpain 3b [ Maylandia zebra (zebra mbuna) ]

Gene ID: 101463601, updated on 8-Mar-2024

Summary

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Gene symbol
capn3b
Gene description
calpain 3b
See related
Ensembl:ENSMZEG00005028024
Gene type
protein coding
RefSeq status
MODEL
Organism
Maylandia zebra
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
104 current M_zebra_UMD2a (GCF_000238955.4) Unplaced Scaffold NW_020192500.1 (213078..229048)
101 previous assembly MetZeb1.1 (GCF_000238955.1) Unplaced Scaffold NW_004531857.1 (208746..224749)

NW_020192500.1Genomic Context describing neighboring genes Neighboring gene macoilin-1 Neighboring gene nuclear receptor binding protein 1 Neighboring gene zinc finger protein 106b Neighboring gene churchill domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Maylandia zebra Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference M_zebra_UMD2a Primary Assembly

Genomic

  1. NW_020192500.1 Reference M_zebra_UMD2a Primary Assembly

    Range
    213078..229048
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004568730.2 → XP_004568787.1  calpain-3

    UniProtKB/TrEMBL
    A0A3P9DTJ5
    Related
    ENSMZEP00005037572.1, ENSMZET00005038881.1
    Conserved Domains (5) summary
    COG5126
    Location:673 → 761
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd00051
    Location:646 → 700
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:78 → 372
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:386 → 536
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:540 → 602
    Calpain_u2; Unstructured region on Calpain-3
Nucleotide Protein
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