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CRKL CRK like proto-oncogene, adaptor protein [ Dasypus novemcinctus (nine-banded armadillo) ]

Gene ID: 101434926, updated on 8-Mar-2024

Summary

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Gene symbol
CRKL
Gene description
CRK like proto-oncogene, adaptor protein
See related
Ensembl:ENSDNOG00000046164
Gene type
protein coding
RefSeq status
MODEL
Organism
Dasypus novemcinctus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Xenarthra; Cingulata; Dasypodidae; Dasypus
Orthologs
human mouse all
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Genomic context

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See CRKL in Genome Data Viewer
Location:
chromosome: 19
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_07 current mDasNov1.hap2 (GCF_030445035.1) 19 NC_080691.1 (49096088..49127503)
102 previous assembly Dasnov3.0 (GCF_000208655.1) Unplaced Scaffold NW_004482235.1 (64022..95422)

Chromosome 19 - NC_080691.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol 4-kinase alpha Neighboring gene vimentin-like Neighboring gene synaptosome associated protein 29 Neighboring gene leucine zipper like post translational regulator 1 Neighboring gene THAP domain containing 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
crk-like protein
Names
v-crk sarcoma virus CT10 oncogene homolog (avian)-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030445035.1-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mDasNov1.hap2

Genomic

  1. NC_080691.1 Reference mDasNov1.hap2

    Range
    49096088..49127503
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004466470.2 → XP_004466527.1  crk-like protein isoform X2

    Related
    ENSDNOP00000029480.1
    Conserved Domains (3) summary
    cd09926
    Location:6 → 106
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:126 → 180
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:237 → 293
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

  2. XM_004466469.3 → XP_004466526.1  crk-like protein isoform X1

    Conserved Domains (3) summary
    cd09926
    Location:6 → 106
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:126 → 180
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cl17036
    Location:237 → 282
    SH3; Src Homology 3 domain superfamily

  3. XM_058281763.1 → XP_058137746.1  crk-like protein isoform X3

Nucleotide Protein
Heading Accession and Version

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