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DGKA diacylglycerol kinase alpha [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101382146, updated on 18-Sep-2024

Summary

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Gene symbol
DGKA
Gene description
diacylglycerol kinase alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Orthologs
human mouse all
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Genomic context

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See DGKA in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450410.1 (432165..454128)

NW_004450410.1Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase D-like Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene premelanosome protein Neighboring gene cyclin dependent kinase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004450410.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450410.1 Reference Oros_1.0 Primary Assembly

    Range
    432165..454128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004401638.1 → XP_004401695.1  diacylglycerol kinase alpha isoform X2

    See identical proteins and their annotated locations for XP_004401695.1

    UniProtKB/TrEMBL
    A0A2U3W186
    Conserved Domains (6) summary
    smart00045
    Location:518 → 699
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:376 → 497
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:112 → 181
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:4 → 108
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20890
    Location:268 → 329
    C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins
    cl00040
    Location:199 → 259
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  2. XM_004401637.2 → XP_004401694.1  diacylglycerol kinase alpha isoform X2

    See identical proteins and their annotated locations for XP_004401694.1

    UniProtKB/TrEMBL
    A0A2U3W186
    Conserved Domains (6) summary
    smart00045
    Location:518 → 699
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:376 → 497
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:112 → 181
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:4 → 108
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20890
    Location:268 → 329
    C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins
    cl00040
    Location:199 → 259
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  3. XM_012562832.1 → XP_012418286.1  diacylglycerol kinase alpha isoform X1

    Conserved Domains (7) summary
    smart00045
    Location:592 → 773
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:450 → 571
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:450 → 795
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00051
    Location:186 → 255
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:278 → 326
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:187 → 251
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:80 → 182
    DAG_kinase_N; Diacylglycerol kinase N-terminus
Nucleotide Protein
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