U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

C1R complement C1r [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101377329, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
C1R
Gene description
complement C1r
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See C1R in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450607.1 (754100..763238)

NW_004450607.1Genomic Context describing neighboring genes Neighboring gene retinol binding protein 5 Neighboring gene complement C1r subcomponent like Neighboring gene complement C1s

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_004450607.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
complement C1r subcomponent

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450607.1 Reference Oros_1.0 Primary Assembly

    Range
    754100..763238
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012564948.1 → XP_012420402.1  complement C1r subcomponent isoform X4

    Conserved Domains (5) summary
    smart00020
    Location:388 → 622
    Tryp_SPc; Trypsin-like serine protease
    smart00042
    Location:27 → 138
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    cd00190
    Location:389 → 624
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:234 → 296
    Sushi; Sushi repeat (SCR repeat)
    cl00049
    Location:153 → 227
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  2. XM_004407627.2 → XP_004407684.1  complement C1r subcomponent isoform X2

    UniProtKB/TrEMBL
    A0A2U3WG63
    Conserved Domains (6) summary
    smart00020
    Location:463 → 697
    Tryp_SPc; Trypsin-like serine protease
    smart00042
    Location:27 → 138
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    cd00190
    Location:464 → 699
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:309 → 371
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:193 → 302
    CUB; CUB domain
    pfam14670
    Location:161 → 189
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_012564947.1 → XP_012420401.1  complement C1r subcomponent isoform X3

    Conserved Domains (6) summary
    smart00020
    Location:429 → 663
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:16 → 106
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:430 → 665
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:275 → 337
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:159 → 268
    CUB; CUB domain
    pfam14670
    Location:127 → 155
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  4. XM_004407626.1 → XP_004407683.1  complement C1r subcomponent isoform X1

    UniProtKB/TrEMBL
    A0A2U3WG57
    Conserved Domains (6) summary
    smart00020
    Location:471 → 705
    Tryp_SPc; Trypsin-like serine protease
    smart00042
    Location:35 → 146
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    cd00190
    Location:472 → 707
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:317 → 379
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:201 → 310
    CUB; CUB domain
    pfam14670
    Location:169 → 197
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.