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PKD1 polycystin 1, transient receptor potential channel interacting [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101372189, updated on 8-Mar-2024

Summary

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Gene symbol
PKD1
Gene description
polycystin 1, transient receptor potential channel interacting
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Orthologs
human mouse all
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Genomic context

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See PKD1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
46
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450442.1 (1807028..1847511, complement)

NW_004450442.1Genomic Context describing neighboring genes Neighboring gene nth like DNA glycosylase 1 Neighboring gene TSC complex subunit 2 Neighboring gene coiled-coil-helix-coiled-coil-helix domain-containing protein 2 pseudogene Neighboring gene RAB26, member RAS oncogene family

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004450442.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in kidney development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
polycystin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450442.1 Reference Oros_1.0 Primary Assembly

    Range
    1807028..1847511 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004403161.1 → XP_004403218.1  polycystin-1 isoform X2

    UniProtKB/TrEMBL
    A0A2U3W568
    Conserved Domains (13) summary
    cd00037
    Location:418 → 531
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:97 → 2731
    PCC; polycystin cation channel protein
    smart00303
    Location:3012 → 3061
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:32 → 71
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125 → 177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:1476 → 1543
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    COG4886
    Location:50 → 128
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd01752
    Location:3119 → 3238
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    sd00031
    Location:70 → 92
    LRR_1; leucine-rich repeat [structural motif]
    pfam00801
    Location:1551 → 1620
    PKD; PKD domain
    pfam08016
    Location:3711 → 4115
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93 → 128
    LRR_4; Leucine Rich repeats (2 copies)
    cl02568
    Location:177 → 265
    WSC; WSC domain

  2. XM_012563356.1 → XP_012418810.1  polycystin-1 isoform X1

    Conserved Domains (13) summary
    cd00037
    Location:418 → 531
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:97 → 2731
    PCC; polycystin cation channel protein
    smart00303
    Location:3012 → 3061
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:32 → 71
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125 → 177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:1476 → 1543
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    COG4886
    Location:50 → 128
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd01752
    Location:3119 → 3238
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    sd00031
    Location:70 → 92
    LRR_1; leucine-rich repeat [structural motif]
    pfam00801
    Location:1551 → 1620
    PKD; PKD domain
    pfam08016
    Location:3713 → 4117
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93 → 128
    LRR_4; Leucine Rich repeats (2 copies)
    cl02568
    Location:177 → 265
    WSC; WSC domain
Nucleotide Protein
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