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CHRNA1 cholinergic receptor nicotinic alpha 1 subunit [ Trichechus manatus latirostris (Florida manatee) ]

Gene ID: 101360577, updated on 8-Mar-2024

Summary

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Gene symbol
CHRNA1
Gene description
cholinergic receptor nicotinic alpha 1 subunit
See related
EnsemblRapid:ENSTMLG00000012023
Gene type
protein coding
RefSeq status
MODEL
Organism
Trichechus manatus latirostris (sub-species: latirostris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus
Orthologs
human mouse all
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Genomic context

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See CHRNA1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_01 current TriManLat1.0 (GCF_000243295.1) Unplaced Scaffold NW_004443973.1 (9634106..9652111)

NW_004443973.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L31 pseudogene Neighboring gene chimerin 1 Neighboring gene U6 spliceosomal RNA Neighboring gene WAS/WASL interacting protein family member 1 Neighboring gene ras-related protein Rap-1b pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004443973 Unplaced Scaffold Reference TriManLat1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetylcholine receptor subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000243295.1-RS_2024_01

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TriManLat1.0 Primary Assembly

Genomic

  1. NW_004443973.1 Reference TriManLat1.0 Primary Assembly

    Range
    9634106..9652111
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004375490.3 → XP_004375547.1  acetylcholine receptor subunit alpha

    UniProtKB/TrEMBL
    A0A2Y9DJ40
    Related
    ENSTMLP00000017217.1, ENSTMLT00000018453.1
    Conserved Domains (3) summary
    TIGR00860
    Location:21 → 447
    LIC; Cation transporter family protein
    pfam02931
    Location:24 → 231
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:238 → 446
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
Nucleotide Protein
Heading Accession and Version

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