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PLEC plectin [ Trichechus manatus latirostris (Florida manatee) ]

Gene ID: 101348801, updated on 8-Mar-2024

Summary

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Gene symbol
PLEC
Gene description
plectin
See related
EnsemblRapid:ENSTMLG00000008980
Gene type
protein coding
RefSeq status
MODEL
Organism
Trichechus manatus latirostris (sub-species: latirostris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus
Orthologs
human mouse all
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Genomic context

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See PLEC in Genome Data Viewer
Location:
chromosome: Un
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2024_01 current TriManLat1.0 (GCF_000243295.1) Unplaced Scaffold NW_004444121.1 (4294766..4353332, complement)

NW_004444121.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor binding protein 2 Neighboring gene epiplakin 1 Neighboring gene poly(ADP-ribose) polymerase family member 10 Neighboring gene glutamate ionotropic receptor NMDA type subunit associated protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004444121 Unplaced Scaffold Reference TriManLat1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intermediate filament cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in wound healing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plectin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000243295.1-RS_2024_01

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TriManLat1.0 Primary Assembly

Genomic

  1. NW_004444121.1 Reference TriManLat1.0 Primary Assembly

    Range
    4294766..4353332 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023741643.1 → XP_023597411.1  plectin isoform X2

    UniProtKB/TrEMBL
    A0A2Y9RUZ6
    Related
    ENSTMLP00000014987.1, ENSTMLT00000016076.1
    Conserved Domains (6) summary
    smart00250
    Location:3367 → 3404
    PLEC; Plectin repeat
    COG5069
    Location:64 → 286
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:638 → 816
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4059 → 4098
    Plectin; Plectin repeat
    cl25732
    Location:973 → 1722
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1359 → 1963
    Neuromodulin_N; Gap junction protein N-terminal region

  2. XM_023741642.1 → XP_023597410.1  plectin isoform X1

    UniProtKB/TrEMBL
    A0A2Y9RR12
    Related
    ENSTMLP00000015109.1, ENSTMLT00000016203.1
    Conserved Domains (7) summary
    smart00250
    Location:3482 → 3519
    PLEC; Plectin repeat
    COG5069
    Location:184 → 401
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:753 → 931
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4174 → 4213
    Plectin; Plectin repeat
    pfam03501
    Location:7 → 99
    S10_plectin; Plectin/S10 domain
    cl25732
    Location:1088 → 1837
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1474 → 2078
    Neuromodulin_N; Gap junction protein N-terminal region

  3. XM_023741644.1 → XP_023597412.1  plectin isoform X3

    UniProtKB/TrEMBL
    A0A2Y9RS80
    Related
    ENSTMLP00000015170.1, ENSTMLT00000016266.1
    Conserved Domains (6) summary
    smart00250
    Location:3340 → 3377
    PLEC; Plectin repeat
    COG5069
    Location:36 → 259
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:611 → 789
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4032 → 4071
    Plectin; Plectin repeat
    cl25732
    Location:946 → 1695
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1332 → 1936
    Neuromodulin_N; Gap junction protein N-terminal region

  4. XM_023741645.1 → XP_023597413.1  plectin isoform X4

    UniProtKB/TrEMBL
    A0A2Y9S061
    Related
    ENSTMLP00000015269.1, ENSTMLT00000016374.1
    Conserved Domains (6) summary
    smart00250
    Location:3349 → 3386
    PLEC; Plectin repeat
    COG5069
    Location:51 → 268
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:620 → 798
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4041 → 4080
    Plectin; Plectin repeat
    cl25732
    Location:955 → 1704
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1341 → 1945
    Neuromodulin_N; Gap junction protein N-terminal region

  5. XM_023741646.1 → XP_023597414.1  plectin isoform X5

    UniProtKB/TrEMBL
    A0A2Y9RZ75
    Related
    ENSTMLP00000015410.1, ENSTMLT00000016527.1
    Conserved Domains (6) summary
    smart00250
    Location:3340 → 3377
    PLEC; Plectin repeat
    COG5069
    Location:42 → 259
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:611 → 789
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:4032 → 4071
    Plectin; Plectin repeat
    cl25732
    Location:946 → 1695
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:1332 → 1936
    Neuromodulin_N; Gap junction protein N-terminal region
Nucleotide Protein
Heading Accession and Version

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