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SMPD3 sphingomyelin phosphodiesterase 3 [ Orcinus orca (killer whale) ]

Gene ID: 101287560, updated on 8-Mar-2024

Summary

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Gene symbol
SMPD3
Gene description
sphingomyelin phosphodiesterase 3
See related
EnsemblRapid:ENSOORG00010013630
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See SMPD3 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 20 NC_064578.1 (18140657..18222618)

Chromosome 20 - NC_064578.1Genomic Context describing neighboring genes Neighboring gene cadherin 3 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12-like Neighboring gene uncharacterized LOC117202587 Neighboring gene ZFP90 zinc finger protein Neighboring gene uncharacterized LOC117202585 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene COMM domain-containing protein 6-like Neighboring gene ras GTPase-activating protein-binding protein 1-like Neighboring gene protein arginine methyltransferase 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064578.1 Chromosome 20 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sphingomyelin phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in sphingomyelin metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingomyelin phosphodiesterase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064578.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    18140657..18222618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033434231.2 → XP_033290122.1  sphingomyelin phosphodiesterase 3 isoform X1

    Conserved Domains (1) summary
    cd09078
    Location:334 → 616
    nSMase; Neutral sphingomyelinases (nSMase) catalyze the hydrolysis of sphingomyelin in biological membranes to ceramide and phosphorylcholine

  2. XM_033434233.2 → XP_033290124.1  sphingomyelin phosphodiesterase 3 isoform X3

    Related
    ENSOORP00010017539.1, ENSOORT00010020216.1
    Conserved Domains (1) summary
    cd09078
    Location:334 → 644
    nSMase; Neutral sphingomyelinases (nSMase) catalyze the hydrolysis of sphingomyelin in biological membranes to ceramide and phosphorylcholine

  3. XM_049703982.1 → XP_049559939.1  sphingomyelin phosphodiesterase 3 isoform X2

  4. XM_049703981.1 → XP_049559938.1  sphingomyelin phosphodiesterase 3 isoform X1

Nucleotide Protein
Heading Accession and Version

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