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PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [ Orcinus orca (killer whale) ]

Gene ID: 101285400, updated on 8-Mar-2024

Summary

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Gene symbol
PFKFB4
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
See related
EnsemblRapid:ENSOORG00010017553
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See PFKFB4 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 10 NC_064568.1 (39373745..39421115)

Chromosome 10 - NC_064568.1Genomic Context describing neighboring genes Neighboring gene collagen type VII alpha 1 chain Neighboring gene urocortin 2 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene shisa family member 5 Neighboring gene three prime repair exonuclease 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064568.1 Chromosome 10 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064568.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    39373745..39421115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033413160.2 → XP_033269051.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:344 → 530
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:127 → 341
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_033413162.2 → XP_033269053.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X2

    Conserved Domains (2) summary
    pfam00300
    Location:344 → 530
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:127 → 341
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_033413165.2 → XP_033269056.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X3

    Conserved Domains (2) summary
    pfam00300
    Location:252 → 438
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 249
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_004283899.4 → XP_004283947.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X5

    Related
    ENSOORP00010023173.1, ENSOORT00010026313.1
    Conserved Domains (2) summary
    pfam00300
    Location:252 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 249
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_049716197.1 → XP_049572154.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X4

RNA

  1. XR_007479766.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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