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PTGIS prostaglandin I2 synthase [ Orcinus orca (killer whale) ]

Gene ID: 101285307, updated on 8-Mar-2024

Summary

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Gene symbol
PTGIS
Gene description
prostaglandin I2 synthase
See related
EnsemblRapid:ENSOORG00010005548
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See PTGIS in Genome Data Viewer
Location:
chromosome: 16
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 16 NC_064574.1 (12637013..12680190)

Chromosome 16 - NC_064574.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC125961348 Neighboring gene uncharacterized LOC125961350 Neighboring gene beta-1,4-galactosyltransferase 5 Neighboring gene potassium voltage-gated channel subfamily B member 1 Neighboring gene somatomedin-B and thrombospondin type-1 domain-containing protein-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064574.1 Chromosome 16 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables prostaglandin-I synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in prostaglandin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostacyclin synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064574.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    12637013..12680190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004282888.3 → XP_004282936.1  prostacyclin synthase isoform X4

    Related
    ENSOORP00010006483.1, ENSOORT00010007983.1
    Conserved Domains (1) summary
    cl12078
    Location:27 → 494
    p450; Cytochrome P450

  2. XM_033411200.2 → XP_033267091.1  prostacyclin synthase isoform X1

    Conserved Domains (1) summary
    cd20634
    Location:77 → 518
    PGIS_CYP8A1; prostacyclin Synthase, also called cytochrome P450 family 8, subfamily A, polypeptide 1

  3. XM_049698664.1 → XP_049554621.1  prostacyclin synthase isoform X3

  4. XM_049698663.1 → XP_049554620.1  prostacyclin synthase isoform X2

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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