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L2HGDH L-2-hydroxyglutarate dehydrogenase [ Orcinus orca (killer whale) ]

Gene ID: 101284995, updated on 8-Mar-2024

Summary

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Gene symbol
L2HGDH
Gene description
L-2-hydroxyglutarate dehydrogenase
See related
EnsemblRapid:ENSOORG00010014769
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See L2HGDH in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 2 NC_064560.1 (151544456..151599876, complement)

Chromosome 2 - NC_064560.1Genomic Context describing neighboring genes Neighboring gene valosin containing protein lysine methyltransferase Neighboring gene SOS Ras/Rho guanine nucleotide exchange factor 2 Neighboring gene U1 spliceosomal RNA Neighboring gene histone PARylation factor 1-like Neighboring gene distal membrane arm assembly component 2 like Neighboring gene cyclin dependent kinase like 1 Neighboring gene uncharacterized LOC125963567 Neighboring gene transfer RNA glycine (anticodon UCC)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064560.1 Chromosome 2 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables (S)-2-hydroxy-acid oxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 2-hydroxyglutarate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
L-2-hydroxyglutarate dehydrogenase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064560.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    151544456..151599876 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_049706315.1 → XP_049562272.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X3

  2. XM_049706314.1 → XP_049562271.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X3

  3. XM_049706316.1 → XP_049562273.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X5

  4. XM_033428463.2 → XP_033284354.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X2

    Conserved Domains (1) summary
    PRK11728
    Location:164 → 536
    PRK11728; L-2-hydroxyglutarate oxidase

  5. XM_033428464.2 → XP_033284355.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X4

    Conserved Domains (1) summary
    PRK11728
    Location:164 → 504
    PRK11728; L-2-hydroxyglutarate oxidase

  6. XM_004270037.3 → XP_004270085.2  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X1

    Related
    ENSOORP00010019129.1, ENSOORT00010021943.1
    Conserved Domains (1) summary
    PRK11728
    Location:164 → 560
    PRK11728; L-2-hydroxyglutarate oxidase
Nucleotide Protein
Heading Accession and Version

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