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PCK1 phosphoenolpyruvate carboxykinase 1 [ Orcinus orca (killer whale) ]

Gene ID: 101284360, updated on 8-Mar-2024

Summary

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Gene symbol
PCK1
Gene description
phosphoenolpyruvate carboxykinase 1
See related
EnsemblRapid:ENSOORG00010013434
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See PCK1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 16 NC_064574.1 (6196456..6202011, complement)

Chromosome 16 - NC_064574.1Genomic Context describing neighboring genes Neighboring gene prostate transmembrane protein, androgen induced 1 Neighboring gene Z-DNA binding protein 1 Neighboring gene CCCTC-binding factor like Neighboring gene RNA binding motif protein 38

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064574.1 Chromosome 16 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphoenolpyruvate carboxykinase, cytosolic [GTP]

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064574.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    6196456..6202011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004282306.4 → XP_004282354.1  phosphoenolpyruvate carboxykinase, cytosolic [GTP]

    See identical proteins and their annotated locations for XP_004282354.1

    Related
    ENSOORP00010017240.1, ENSOORT00010019897.1
    Conserved Domains (1) summary
    cd00819
    Location:27 → 615
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
Nucleotide Protein
Heading Accession and Version

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