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ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 [ Orcinus orca (killer whale) ]

Gene ID: 101284219, updated on 8-Mar-2024

Summary

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Gene symbol
ENPP2
Gene description
ectonucleotide pyrophosphatase/phosphodiesterase 2
See related
EnsemblRapid:ENSOORG00010005792
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See ENPP2 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 17 NC_064575.1 (68454894..68562997, complement)

Chromosome 17 - NC_064575.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117199668 Neighboring gene cellular communication network factor 3 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene uncharacterized LOC117199667 Neighboring gene TATA-box binding protein associated factor 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064575.1 Chromosome 17 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alkylglycerophosphoethanolamine phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lysophospholipase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphodiesterase I activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables polysaccharide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables scavenger receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in estrous cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylcholine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ectonucleotide pyrophosphatase/phosphodiesterase family member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064575.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    68454894..68562997 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_049700671.1 → XP_049556628.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X4

  2. XM_033419908.2 → XP_033275799.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X3

    Related
    ENSOORP00010006845.1, ENSOORT00010008367.1
    Conserved Domains (3) summary
    smart00201
    Location:53 → 94
    SO; Somatomedin B -like domains
    smart00477
    Location:636 → 866
    NUC; DNA/RNA non-specific endonuclease
    pfam01663
    Location:162 → 474
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

  3. XM_004265360.3 → XP_004265408.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X9

    Related
    ENSOORP00010006837.1, ENSOORT00010008359.1
    Conserved Domains (4) summary
    smart00201
    Location:57 → 98
    SO; Somatomedin B -like domains
    smart00477
    Location:667 → 897
    NUC; DNA/RNA non-specific endonuclease
    pfam01663
    Location:166 → 530
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase
    cd16018
    Location:164 → 570
    Enpp; Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin

  4. XM_033419912.2 → XP_033275803.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X7

    Conserved Domains (3) summary
    smart00201
    Location:57 → 98
    SO; Somatomedin B -like domains
    smart00477
    Location:598 → 828
    NUC; DNA/RNA non-specific endonuclease
    cd16018
    Location:164 → 476
    Enpp; Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin

  5. XM_033419911.2 → XP_033275802.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X6

    Conserved Domains (3) summary
    smart00201
    Location:57 → 98
    SO; Somatomedin B -like domains
    smart00477
    Location:611 → 841
    NUC; DNA/RNA non-specific endonuclease
    pfam01663
    Location:166 → 478
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

  6. XM_033419909.2 → XP_033275800.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X2

    Conserved Domains (3) summary
    smart00201
    Location:57 → 98
    SO; Somatomedin B -like domains
    smart00477
    Location:636 → 866
    NUC; DNA/RNA non-specific endonuclease
    pfam01663
    Location:166 → 478
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase

  7. XM_004265362.4 → XP_004265410.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X5

    Conserved Domains (4) summary
    smart00201
    Location:57 → 98
    SO; Somatomedin B -like domains
    smart00477
    Location:615 → 845
    NUC; DNA/RNA non-specific endonuclease
    pfam01663
    Location:166 → 478
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase
    cd16018
    Location:164 → 518
    Enpp; Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin

  8. XM_004265361.4 → XP_004265409.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X1

    Related
    ENSOORP00010006842.1, ENSOORT00010008364.1
    Conserved Domains (4) summary
    smart00201
    Location:57 → 98
    SO; Somatomedin B -like domains
    smart00477
    Location:640 → 870
    NUC; DNA/RNA non-specific endonuclease
    pfam01663
    Location:166 → 478
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase
    cd16018
    Location:164 → 518
    Enpp; Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin

  9. XM_049700672.1 → XP_049556629.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X8

Nucleotide Protein
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