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HPSE heparanase [ Orcinus orca (killer whale) ]

Gene ID: 101283118, updated on 8-Mar-2024

Summary

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Gene symbol
HPSE
Gene description
heparanase
See related
EnsemblRapid:ENSOORG00010022812
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See HPSE in Genome Data Viewer
Location:
chromosome: 4
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 4 NC_064562.1 (42163994..42198023)

Chromosome 4 - NC_064562.1Genomic Context describing neighboring genes Neighboring gene abraxas 1, BRCA1 A complex subunit Neighboring gene mitochondrial ribosomal protein S18C Neighboring gene helicase, POLQ like Neighboring gene coenzyme Q2, polyprenyltransferase Neighboring gene uncharacterized LOC101283949

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064562.1 Chromosome 4 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
heparanase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064562.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    42163994..42198023
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004282160.4 → XP_004282208.1  heparanase isoform X3

    See identical proteins and their annotated locations for XP_004282208.1

    Conserved Domains (1) summary
    pfam03662
    Location:170 → 329
    Glyco_hydro_79n; Glycosyl hydrolase family 79, N-terminal domain

  2. XM_033409979.2 → XP_033265870.1  heparanase isoform X2

    Related
    ENSOORP00010030252.1, ENSOORT00010034147.1
    Conserved Domains (1) summary
    pfam03662
    Location:178 → 311
    Glyco_hydro_79n; Glycosyl hydrolase family 79, N-terminal domain

  3. XM_004282158.3 → XP_004282206.1  heparanase isoform X1

    See identical proteins and their annotated locations for XP_004282206.1

    Related
    ENSOORP00010030251.1, ENSOORT00010034146.1
    Conserved Domains (1) summary
    pfam03662
    Location:170 → 369
    Glyco_hydro_79n; Glycosyl hydrolase family 79, N-terminal domain
Nucleotide Protein
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