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HAGH hydroxyacylglutathione hydrolase [ Orcinus orca (killer whale) ]

Gene ID: 101280833, updated on 8-Mar-2024

Summary

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Gene symbol
HAGH
Gene description
hydroxyacylglutathione hydrolase
See related
EnsemblRapid:ENSOORG00010012524
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See HAGH in Genome Data Viewer
Location:
chromosome: 16
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 16 NC_064574.1 (50913733..50941699, complement)

Chromosome 16 - NC_064574.1Genomic Context describing neighboring genes Neighboring gene NUBP iron-sulfur cluster assembly factor 2, cytosolic Neighboring gene insulin like growth factor binding protein acid labile subunit Neighboring gene fumarylacetoacetate hydrolase domain containing 1 Neighboring gene meiosis specific with OB-fold Neighboring gene heparan sulfate-glucosamine 3-sulfotransferase 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064574.1 Chromosome 16 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxyacylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxyacylglutathione hydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064574.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    50913733..50941699 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_049699648.1 → XP_049555605.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X3

  2. XM_033429185.2 → XP_033285076.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X5

    Related
    ENSOORP00010016022.1, ENSOORT00010018512.1
    Conserved Domains (1) summary
    cd07723
    Location:55 → 145
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

  3. XM_033429184.2 → XP_033285075.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X2

    Conserved Domains (1) summary
    PLN02469
    Location:50 → 271
    PLN02469; hydroxyacylglutathione hydrolase

  4. XM_004270324.4 → XP_004270372.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X1

    Related
    ENSOORP00010016027.1, ENSOORT00010018517.1
    Conserved Domains (1) summary
    PLN02469
    Location:50 → 305
    PLN02469; hydroxyacylglutathione hydrolase

  5. XM_049699649.1 → XP_049555606.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X4

Nucleotide Protein
Heading Accession and Version

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