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STAT5A signal transducer and activator of transcription 5A [ Orcinus orca (killer whale) ]

Gene ID: 101280792, updated on 11-Apr-2024

Summary

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Gene symbol
STAT5A
Gene description
signal transducer and activator of transcription 5A
See related
EnsemblRapid:ENSOORG00010018655
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See STAT5A in Genome Data Viewer
Location:
chromosome: 19
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 19 NC_064577.1 (40845938..40865430, complement)

Chromosome 19 - NC_064577.1Genomic Context describing neighboring genes Neighboring gene caveolae associated protein 1 Neighboring gene signal transducer and activator of transcription 3 Neighboring gene signal transducer and activator of transcription 5B Neighboring gene 3-hydroxyisobutyrate dehydrogenase, mitochondrial-like Neighboring gene GH3 domain containing Neighboring gene hypocretin neuropeptide precursor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064577.1 Chromosome 19 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 5A
Names
signal transducer and activator of transcription factor 5A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064577.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    40845938..40865430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033411096.2 → XP_033266987.1  signal transducer and activator of transcription 5A isoform X2

    Conserved Domains (4) summary
    cd10421
    Location:571 → 710
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 487
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  2. XM_004282814.4 → XP_004282862.2  signal transducer and activator of transcription 5A isoform X1

    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  3. XM_033411095.2 → XP_033266986.1  signal transducer and activator of transcription 5A isoform X1

    Related
    ENSOORP00010024560.1, ENSOORT00010027937.1
    Conserved Domains (4) summary
    cd10421
    Location:573 → 712
    SH2_STAT5a; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain

  4. XM_033411097.2 → XP_033266988.1  signal transducer and activator of transcription 5A isoform X3

    Conserved Domains (4) summary
    cd16855
    Location:139 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 489
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:4 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 640
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein
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