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PLCD1 phospholipase C delta 1 [ Orcinus orca (killer whale) ]

Gene ID: 101279487, updated on 8-Mar-2024

Summary

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Gene symbol
PLCD1
Gene description
phospholipase C delta 1
See related
EnsemblRapid:ENSOORG00010015790
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See PLCD1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 10 NC_064568.1 (47723472..47745511)

Chromosome 10 - NC_064568.1Genomic Context describing neighboring genes Neighboring gene acetyl-CoA acyltransferase 1 Neighboring gene DLEC1 cilia and flagella associated protein Neighboring gene translation initiation factor eIF-2B subunit delta-like Neighboring gene villin like Neighboring gene CTD small phosphatase like Neighboring gene uncharacterized LOC117195873

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064568.1 Chromosome 10 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064568.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    47723472..47745511
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004277909.3 → XP_004277957.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

    Related
    ENSOORP00010020573.1, ENSOORT00010023522.1
    Conserved Domains (8) summary
    cd00275
    Location:629 → 752
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:295 → 596
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    PLN02228
    Location:220 → 755
    PLN02228; Phosphoinositide phospholipase C
    cd13363
    Location:22 → 139
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    pfam00169
    Location:30 → 130
    PH; PH domain
    pfam09279
    Location:213 → 295
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam13499
    Location:145 → 205
    EF-hand_7; EF-hand domain pair
    pfam14788
    Location:159 → 208
    EF-hand_10; EF hand

  2. XM_033402152.2 → XP_033258043.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

    Related
    ENSOORP00010020568.1, ENSOORT00010023516.1
    Conserved Domains (4) summary
    cd00275
    Location:690 → 813
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:356 → 657
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:83 → 200
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:205 → 344
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)
Nucleotide Protein
Heading Accession and Version

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