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MTM1 myotubularin 1 [ Orcinus orca (killer whale) ]

Gene ID: 101279268, updated on 8-Mar-2024

Summary

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Gene symbol
MTM1
Gene description
myotubularin 1
See related
EnsemblRapid:ENSOORG00010011302
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See MTM1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) X NC_064580.1 (128475882..128574242)

Chromosome X - NC_064580.1Genomic Context describing neighboring genes Neighboring gene spermatogenesis-associated protein 17-like Neighboring gene mastermind like domain containing 1 Neighboring gene uncharacterized LOC125963122 Neighboring gene myotubularin related protein 1 Neighboring gene CD99 molecule like 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064580.1 Chromosome X Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitochondrion distribution IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle cell cellular homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myotubularin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064580.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    128475882..128574242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033413544.2 → XP_033269435.1  myotubularin isoform X3

    Conserved Domains (2) summary
    cd13355
    Location:36 → 135
    PH-GRAM_MTM1; Myotubularian 1 protein (MTM1) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam06602
    Location:154 → 478
    Myotub-related; Myotubularin-like phosphatase domain

  2. XM_004284092.4 → XP_004284140.1  myotubularin isoform X1

    Conserved Domains (2) summary
    cd13355
    Location:44 → 143
    PH-GRAM_MTM1; Myotubularian 1 protein (MTM1) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam06602
    Location:162 → 486
    Myotub-related; Myotubularin-like phosphatase domain

  3. XM_033413547.2 → XP_033269438.1  myotubularin isoform X1

    Conserved Domains (2) summary
    cd13355
    Location:44 → 143
    PH-GRAM_MTM1; Myotubularian 1 protein (MTM1) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam06602
    Location:162 → 486
    Myotub-related; Myotubularin-like phosphatase domain

  4. XM_049705026.1 → XP_049560983.1  myotubularin isoform X3

  5. XM_049705025.1 → XP_049560982.1  myotubularin isoform X1

    Related
    ENSOORP00010014312.1, ENSOORT00010016684.1

  6. XM_033413541.2 → XP_033269432.1  myotubularin isoform X2

    Conserved Domains (2) summary
    cd13355
    Location:44 → 143
    PH-GRAM_MTM1; Myotubularian 1 protein (MTM1) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam06602
    Location:162 → 486
    Myotub-related; Myotubularin-like phosphatase domain

  7. XM_033413542.2 → XP_033269433.1  myotubularin isoform X3

    Conserved Domains (2) summary
    cd13355
    Location:36 → 135
    PH-GRAM_MTM1; Myotubularian 1 protein (MTM1) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam06602
    Location:154 → 478
    Myotub-related; Myotubularin-like phosphatase domain

  8. XM_033413540.2 → XP_033269431.1  myotubularin isoform X1

    Conserved Domains (2) summary
    cd13355
    Location:44 → 143
    PH-GRAM_MTM1; Myotubularian 1 protein (MTM1) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam06602
    Location:162 → 486
    Myotub-related; Myotubularin-like phosphatase domain

  9. XM_033413546.2 → XP_033269437.1  myotubularin isoform X5

    Conserved Domains (2) summary
    cd13355
    Location:44 → 143
    PH-GRAM_MTM1; Myotubularian 1 protein (MTM1) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cl28904
    Location:174 → 421
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  10. XM_033413545.2 → XP_033269436.1  myotubularin isoform X4

    Conserved Domains (2) summary
    pfam06602
    Location:115 → 439
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:18 → 96
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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