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PI4KA phosphatidylinositol 4-kinase alpha [ Orcinus orca (killer whale) ]

Gene ID: 101271039, updated on 8-Mar-2024

Summary

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Gene symbol
PI4KA
Gene description
phosphatidylinositol 4-kinase alpha
See related
EnsemblRapid:ENSOORG00010017132
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See PI4KA in Genome Data Viewer
Location:
chromosome: 15
Exon count:
56
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 15 NC_064573.1 (63502900..63598307)

Chromosome 15 - NC_064573.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC125961187 Neighboring gene uncharacterized LOC117203737 Neighboring gene synaptosome associated protein 29 Neighboring gene WW domain binding protein 1-like Neighboring gene serpin family D member 1 Neighboring gene uncharacterized LOC125961230 Neighboring gene transmembrane protein 191C Neighboring gene HIC ZBTB transcriptional repressor 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064573.1 Chromosome 15 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol 4-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-kinase alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064573.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    63502900..63598307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_049697571.1 → XP_049553528.1  phosphatidylinositol 4-kinase alpha isoform X1

  2. XM_049697572.1 → XP_049553529.1  phosphatidylinositol 4-kinase alpha isoform X3

  3. XM_049697574.1 → XP_049553531.1  phosphatidylinositol 4-kinase alpha isoform X5

  4. XM_049697573.1 → XP_049553530.1  phosphatidylinositol 4-kinase alpha isoform X4

  5. XM_033439618.2 → XP_033295509.1  phosphatidylinositol 4-kinase alpha isoform X2

    Conserved Domains (2) summary
    cd00871
    Location:1541 → 1744
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1805 → 2160
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

  6. XM_004276025.4 → XP_004276073.1  phosphatidylinositol 4-kinase alpha isoform X6

    Related
    ENSOORP00010022513.1, ENSOORT00010025626.1
    Conserved Domains (2) summary
    cd00871
    Location:1541 → 1716
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1777 → 2095
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

RNA

  1. XR_007471535.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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