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PIK3C2G phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [ Orcinus orca (killer whale) ]

Gene ID: 101270703, updated on 8-Mar-2024

Summary

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Gene symbol
PIK3C2G
Gene description
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
See related
EnsemblRapid:ENSOORG00010003060
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See PIK3C2G in Genome Data Viewer
Location:
chromosome: 11
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 11 NC_064569.1 (14483394..14849112)

Chromosome 11 - NC_064569.1Genomic Context describing neighboring genes Neighboring gene transfer RNA arginine (anticodon UCU) Neighboring gene RERG like Neighboring gene ADP-sugar pyrophosphatase-like Neighboring gene phospholipase C zeta 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064569.1 Chromosome 11 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase C2 domain-containing subunit gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064569.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    14483394..14849112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033430304.2 → XP_033286195.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X1

    Conserved Domains (6) summary
    cd06896
    Location:1256 → 1356
    PX_PI3K_C2_gamma; The phosphoinositide binding Phox Homology Domain of the Gamma Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:516 → 683
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd05177
    Location:875 → 1227
    PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
    cl00271
    Location:700 → 868
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:281 → 363
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl14603
    Location:1378 → 1490
    C2; C2 domain

  2. XM_049695083.1 → XP_049551040.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X9

  3. XM_033430311.2 → XP_033286202.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X7

    Conserved Domains (6) summary
    cd06896
    Location:1227 → 1327
    PX_PI3K_C2_gamma; The phosphoinositide binding Phox Homology Domain of the Gamma Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:516 → 683
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd05177
    Location:846 → 1198
    PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
    cl00271
    Location:700 → 839
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:281 → 363
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl14603
    Location:1349 → 1461
    C2; C2 domain

  4. XM_033430307.2 → XP_033286198.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X2

    Conserved Domains (6) summary
    cd06896
    Location:1246 → 1346
    PX_PI3K_C2_gamma; The phosphoinositide binding Phox Homology Domain of the Gamma Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:516 → 673
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd05177
    Location:865 → 1217
    PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
    cl00271
    Location:690 → 858
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:281 → 363
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl14603
    Location:1368 → 1480
    C2; C2 domain

  5. XM_049695079.1 → XP_049551036.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X3

    Related
    ENSOORP00010003280.1, ENSOORT00010004269.1

  6. XM_033430308.2 → XP_033286199.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X4

    Conserved Domains (6) summary
    cd06896
    Location:1235 → 1335
    PX_PI3K_C2_gamma; The phosphoinositide binding Phox Homology Domain of the Gamma Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:516 → 662
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd05177
    Location:854 → 1206
    PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
    cl00271
    Location:679 → 847
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:281 → 363
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl14603
    Location:1357 → 1469
    C2; C2 domain

  7. XM_049695084.1 → XP_049551041.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X10

  8. XM_049695081.1 → XP_049551038.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X5

  9. XM_049695082.1 → XP_049551039.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X8

  10. XM_033430310.2 → XP_033286201.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X6

    Conserved Domains (6) summary
    cd06896
    Location:1256 → 1356
    PX_PI3K_C2_gamma; The phosphoinositide binding Phox Homology Domain of the Gamma Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:516 → 683
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd05177
    Location:875 → 1227
    PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
    cl00271
    Location:700 → 868
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:281 → 363
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl14603
    Location:1378 → 1402
    C2; C2 domain

  11. XM_033430306.2 → XP_033286197.1  phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X1

    Conserved Domains (6) summary
    cd06896
    Location:1256 → 1356
    PX_PI3K_C2_gamma; The phosphoinositide binding Phox Homology Domain of the Gamma Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:516 → 683
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd05177
    Location:875 → 1227
    PI3Kc_C2_gamma; Catalytic domain of Class II Phosphoinositide 3-kinase gamma
    cl00271
    Location:700 → 868
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...
    cl02484
    Location:281 → 363
    PI3K_rbd; PI3-kinase family, ras-binding domain
    cl14603
    Location:1378 → 1490
    C2; C2 domain
Nucleotide Protein
Heading Accession and Version

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