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DEGS1 delta 4-desaturase, sphingolipid 1 [ Orcinus orca (killer whale) ]

Gene ID: 101269383, updated on 8-Mar-2024

Summary

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Gene symbol
DEGS1
Gene description
delta 4-desaturase, sphingolipid 1
See related
EnsemblRapid:ENSOORG00010011722
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See DEGS1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 1 NC_064559.1 (11390621..11399224, complement)

Chromosome 1 - NC_064559.1Genomic Context describing neighboring genes Neighboring gene nuclear VCP like Neighboring gene 60S acidic ribosomal protein P1-like Neighboring gene uncharacterized LOC117201768 Neighboring gene uncharacterized LOC125963507 Neighboring gene F-box protein 28

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064559.1 Chromosome 1 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sphingolipid delta-4 desaturase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingolipid delta(4)-desaturase DES1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064559.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    11390621..11399224 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004270998.4 → XP_004271046.1  sphingolipid delta(4)-desaturase DES1 isoform X1

    Related
    ENSOORP00010014859.1, ENSOORT00010017279.1
    Conserved Domains (3) summary
    PLN02579
    Location:5 → 314
    PLN02579; sphingolipid delta-4 desaturase
    cd03508
    Location:26 → 315
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
    pfam08557
    Location:6 → 40
    Lipid_DES; Sphingolipid Delta4-desaturase (DES)

  2. XM_033430414.2 → XP_033286305.1  sphingolipid delta(4)-desaturase DES1 isoform X2

    Conserved Domains (1) summary
    cd03508
    Location:1 → 279
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
Nucleotide Protein
Heading Accession and Version

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