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GAME6 GLYCOALKALOID METABOLISM 6 [ Solanum lycopersicum (tomato) ]

Gene ID: 101255011, updated on 5-Nov-2024

Summary

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Gene symbol
GAME6
Gene description
GLYCOALKALOID METABOLISM 6
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Solanum lycopersicum
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Solanum subgen. Lycopersicon
Also known as
CYP72A; SlCYP72A18
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Genomic context

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See GAME6 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_09 current SLM_r2.1 (GCF_036512215.1) 7 NC_090806.1 (59345144..59347265)
103 previous assembly SL3.0 (GCF_000188115.4) 7 NC_015444.3 (57374312..57376448)

Chromosome 7 - NC_090806.1Genomic Context describing neighboring genes Neighboring gene 2-oxoglutarate-dependent dioxygenase 2 Neighboring gene zeatin O-xylosyltransferase-like Neighboring gene U6 spliceosomal RNA Neighboring gene UDP-glucosyltransferase Neighboring gene uncharacterized LOC138337233

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Jasmonate-induced biosynthesis of steroidal glycoalkaloids depends on COI1 proteins in tomato. Abdelkareem A, et al. Biochem Biophys Res Commun, 2017 Jul 22. PMID 28554842
  2. Biosynthesis of antinutritional alkaloids in solanaceous crops is mediated by clustered genes. Itkin M, et al. Science, 2013 Jul 12. PMID 23788733
  3. GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway. Cárdenas PD, et al. Nat Commun, 2016 Feb 15. PMID 26876023, Free PMC Article
  4. Phylogenomic analysis of cytochrome P450 multigene family and their differential expression analysis in Solanum lycopersicum L. suggested tissue specific promoters. Vasav AP, et al. BMC Genomics, 2019 Feb 7. PMID 30732561, Free PMC Article
  5. JRE4 is a master transcriptional regulator of defense-related steroidal glycoalkaloids in tomato. Nakayasu M, et al. Plant J, 2018 Jun. PMID 29569783

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GLYCOALKALOID METABOLISM 6
Names
cytochrome P450 CYP72A219

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001365979.1 → NP_001352908.1  GLYCOALKALOID METABOLISM 6

    Status: VALIDATED

    Source sequence(s)
    AEKE03003143
    UniProtKB/TrEMBL
    A0A3Q7H9W3
    Conserved Domains (1) summary
    cl12078
    Location:14 → 515
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_036512215.1-RS_2024_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference SLM_r2.1 Primary Assembly

Genomic

  1. NC_090806.1 Reference SLM_r2.1 Primary Assembly

    Range
    59345144..59347265
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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