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LARGE2 LARGE xylosyl- and glucuronyltransferase 2 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101141075, updated on 1-Oct-2024

Summary

Gene symbol
LARGE2
Gene description
LARGE xylosyl- and glucuronyltransferase 2
See related
Ensembl:ENSGGOG00000002302
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
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Genomic context

See LARGE2 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 9 NC_073233.2 (52292547..52298882)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 11 NC_073235.1 (55656483..55662804)

Chromosome 9 - NC_073233.2Genomic Context describing neighboring genes Neighboring gene Frey regulator of sperm-oocyte fusion 1 Neighboring gene peroxisomal biogenesis factor 16 Neighboring gene PHD finger protein 21A Neighboring gene filamin-binding LIM protein 1-like

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables xylosyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
xylosyl- and glucuronyltransferase LARGE2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073233.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    52292547..52298882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_055354754.2XP_055210729.1  xylosyl- and glucuronyltransferase LARGE2 isoform X6

  2. XM_055354747.2XP_055210722.1  xylosyl- and glucuronyltransferase LARGE2 isoform X1

  3. XM_063711091.1XP_063567161.1  xylosyl- and glucuronyltransferase LARGE2 isoform X3

  4. XM_004051003.3XP_004051051.1  xylosyl- and glucuronyltransferase LARGE2 isoform X2

    See identical proteins and their annotated locations for XP_004051051.1

    UniProtKB/TrEMBL
    G3QIP8
    Related
    ENSGGOP00000002263.2
    Conserved Domains (2) summary
    cd06431
    Location:97376
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:431664
    Glyco_transf_49; Glycosyl-transferase for dystroglycan
  5. XM_063711092.1XP_063567162.1  xylosyl- and glucuronyltransferase LARGE2 isoform X5

  6. XM_019037757.3XP_018893302.1  xylosyl- and glucuronyltransferase LARGE2 isoform X4

    UniProtKB/TrEMBL
    A0A2I2YZR5
    Related
    ENSGGOP00000040476.1
    Conserved Domains (2) summary
    cd06431
    Location:66345
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:400633
    Glyco_transf_49; Glycosyl-transferase for dystroglycan
  7. XM_063711090.1XP_063567160.1  xylosyl- and glucuronyltransferase LARGE2 isoform X1