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PKLR pyruvate kinase L/R [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101129346, updated on 1-Oct-2024

Summary

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Gene symbol
PKLR
Gene description
pyruvate kinase L/R
See related
Ensembl:ENSGGOG00000001917
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
human mouse all
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Genomic context

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See PKLR in Genome Data Viewer
Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 1 NC_073224.2 (101518990..101530179)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 1 NC_073224.1 (146740866..146752138, complement)

Chromosome 1 - NC_073224.2Genomic Context describing neighboring genes Neighboring gene RUN and SH3 domain containing 1 Neighboring gene putative uncharacterized protein RUSC1-AS1 Neighboring gene farnesyl diphosphate synthase Neighboring gene hyperpolarization activated cyclic nucleotide gated potassium channel 3 Neighboring gene CDC like kinase 2 Neighboring gene secretory carrier membrane protein 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate kinase PKLR
Names
pyruvate kinase, liver and RBC

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073224.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    101518990..101530179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004026915.4 → XP_004026964.1  pyruvate kinase PKLR

    UniProtKB/TrEMBL
    G3QHQ3, G3S6L6
    Related
    ENSGGOP00000023723.2
    Conserved Domains (1) summary
    cd00288
    Location:54 → 542
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
Nucleotide Protein
Heading Accession and Version

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