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INPPL1 inositol polyphosphate phosphatase like 1 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101127569, updated on 10-Oct-2024

Summary

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Gene symbol
INPPL1
Gene description
inositol polyphosphate phosphatase like 1
See related
Ensembl:ENSGGOG00000011295
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
human mouse all
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Genomic context

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See INPPL1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 9 NC_073233.2 (80109649..80125343)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 11 NC_073235.1 (82288291..82304017)

Chromosome 9 - NC_073233.2Genomic Context describing neighboring genes Neighboring gene folate receptor alpha Neighboring gene folate receptor beta Neighboring gene paired like homeobox 2A Neighboring gene docking protein 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol-polyphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of insulin-like growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073233.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    80109649..80125343
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_055356736.2 → XP_055212711.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

  2. XM_055356733.2 → XP_055212708.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

  3. XM_063693349.1 → XP_063549419.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X7

  4. XM_055356739.2 → XP_055212714.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X3

  5. XM_031015989.3 → XP_030871849.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X5

    UniProtKB/TrEMBL
    G3S669
    Conserved Domains (4) summary
    cd09491
    Location:1177 → 1239
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:424 → 727
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    cd10343
    Location:17 → 119
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
    PRK01973
    Location:93 → 181
    PRK01973; septum site-determining protein MinC

  6. XM_055356737.2 → XP_055212712.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2

  7. XM_055356734.2 → XP_055212709.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

  8. XM_031015986.3 → XP_030871846.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X4

    UniProtKB/TrEMBL
    G3S669
    Conserved Domains (4) summary
    cd09491
    Location:1194 → 1256
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:424 → 727
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    cd10343
    Location:17 → 119
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
    PRK01973
    Location:93 → 181
    PRK01973; septum site-determining protein MinC

  9. XM_055356740.2 → XP_055212715.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X6

Nucleotide Protein
Heading Accession and Version

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