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PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101126566, updated on 1-Oct-2024

Summary

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Gene symbol
PFKFB3
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
See related
Ensembl:ENSGGOG00000008683
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
human mouse all
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Genomic context

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See PFKFB3 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 8 NC_073232.2 (15119071..15207802)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 10 NC_073234.1 (15234931..15323721)

Chromosome 8 - NC_073232.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA14 Neighboring gene interleukin 2 receptor subunit alpha Neighboring gene RNA binding motif protein 17 Neighboring gene syntenin-1-like Neighboring gene uncharacterized LOC129525030

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073232.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    15119071..15207802
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019034837.4 → XP_018890382.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X4

    UniProtKB/TrEMBL
    A0A2I2YXY8
    Conserved Domains (2) summary
    pfam01591
    Location:7 → 226
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:229 → 412
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  2. XM_004049029.5 → XP_004049077.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X5

    See identical proteins and their annotated locations for XP_004049077.1

    UniProtKB/TrEMBL
    A0A2I2YE16, A0A2I2YXY8
    Related
    ENSGGOP00000033141.1
    Conserved Domains (2) summary
    pfam01591
    Location:7 → 226
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:229 → 412
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  3. XM_019034838.4 → XP_018890383.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X6

    UniProtKB/TrEMBL
    A0A2I2YXY8
    Conserved Domains (2) summary
    pfam01591
    Location:7 → 226
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:229 → 412
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  4. XM_004049028.5 → XP_004049076.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2

    See identical proteins and their annotated locations for XP_004049076.1

    UniProtKB/TrEMBL
    A0A2I2Z683, A0A2I2ZVY7
    Related
    ENSGGOP00000051394.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_019034835.4 → XP_018890380.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1

    UniProtKB/TrEMBL
    A0A2I2Z683, A0A2I2ZNQ7
    Related
    ENSGGOP00000048928.1
    Conserved Domains (2) summary
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  6. XM_019034836.4 → XP_018890381.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X3

    UniProtKB/TrEMBL
    A0A2I2Z683, A0A2I2ZXU3
    Related
    ENSGGOP00000052009.1
    Conserved Domains (2) summary
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
Nucleotide Protein
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