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SHMT1 serine hydroxymethyltransferase 1 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101125073, updated on 10-Oct-2024

Summary

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Gene symbol
SHMT1
Gene description
serine hydroxymethyltransferase 1
See related
Ensembl:ENSGGOG00000003097
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
human mouse all
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Genomic context

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See SHMT1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 4 NC_073228.2 (83157400..83192790, complement)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 5 NC_073229.1 (81580018..81615594, complement)

Chromosome 4 - NC_073228.2Genomic Context describing neighboring genes Neighboring gene mitochondrial elongation factor 2 Neighboring gene DNA topoisomerase III alpha Neighboring gene SMCR8-C9orf72 complex subunit Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC129533372 Neighboring gene envoplakin like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA regulatory element binding translation repressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to leukemia inhibitory factor IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine hydroxymethyltransferase, cytosolic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073228.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    83157400..83192790 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_055386071.2 → XP_055242046.1  serine hydroxymethyltransferase, cytosolic isoform X2

  2. XM_031010777.3 → XP_030866637.1  serine hydroxymethyltransferase, cytosolic isoform X1

    UniProtKB/TrEMBL
    G3QKR5
    Conserved Domains (1) summary
    PLN03226
    Location:24 → 480
    PLN03226; serine hydroxymethyltransferase; Provisional

  3. XM_055386067.2 → XP_055242042.1  serine hydroxymethyltransferase, cytosolic isoform X1

  4. XM_055386070.2 → XP_055242045.1  serine hydroxymethyltransferase, cytosolic isoform X2

  5. XM_055386069.1 → XP_055242044.1  serine hydroxymethyltransferase, cytosolic isoform X1

  6. XM_055386068.1 → XP_055242043.1  serine hydroxymethyltransferase, cytosolic isoform X1

Nucleotide Protein
Heading Accession and Version

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