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INPPL1 inositol polyphosphate phosphatase like 1 [ Ovis aries (sheep) ]

Gene ID: 101121707, updated on 8-Mar-2024

Summary

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Gene symbol
INPPL1
Gene description
inositol polyphosphate phosphatase like 1
See related
EnsemblRapid:ENSOARG00020017642
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See INPPL1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 15 NC_056068.1 (50557705..50573210)

Chromosome 15 - NC_056068.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132657824 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene folate receptor beta Neighboring gene uncharacterized LOC121816698 Neighboring gene paired like homeobox 2A Neighboring gene ClpB family mitochondrial disaggregase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056068.1 Chromosome 15 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056068.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    50557705..50573210
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042233191.2 → XP_042089125.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3EGL7, W5P3B0
    Conserved Domains (4) summary
    cd09491
    Location:1201 → 1262
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:430 → 733
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    cd10343
    Location:22 → 124
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
    PHA03247
    Location:905 → 1220
    PHA03247; large tegument protein UL36; Provisional

  2. XM_042233188.2 → XP_042089122.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3EGL7, W5P3B0
    Conserved Domains (4) summary
    cd09491
    Location:1201 → 1262
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:430 → 733
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    cd10343
    Location:22 → 124
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
    PHA03247
    Location:905 → 1220
    PHA03247; large tegument protein UL36; Provisional

  3. XM_042233189.2 → XP_042089123.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3EGL7, W5P3B0
    Related
    ENSOARP00020041239.1, ENSOART00020050145.1
    Conserved Domains (4) summary
    cd09491
    Location:1201 → 1262
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:430 → 733
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    cd10343
    Location:22 → 124
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
    PHA03247
    Location:905 → 1220
    PHA03247; large tegument protein UL36; Provisional

  4. XM_042233190.2 → XP_042089124.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3EGL7, W5P3B0
    Conserved Domains (4) summary
    cd09491
    Location:1201 → 1262
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:430 → 733
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    cd10343
    Location:22 → 124
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
    PHA03247
    Location:905 → 1220
    PHA03247; large tegument protein UL36; Provisional

  5. XM_004016291.6 → XP_004016340.3  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P3EGL7, W5P3B0
    Related
    ENSOARP00020022551.1, ENSOART00020027180.2
    Conserved Domains (4) summary
    cd09491
    Location:1201 → 1262
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:430 → 733
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    cd10343
    Location:22 → 124
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
    PHA03247
    Location:905 → 1220
    PHA03247; large tegument protein UL36; Provisional

  6. XM_042233192.2 → XP_042089126.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2

    UniProtKB/TrEMBL
    W5P3B0
    Related
    ENSOARP00020054069.1, ENSOART00020072420.1
    Conserved Domains (4) summary
    cd09491
    Location:1163 → 1224
    SAM_Ship2; SAM domain of Ship2 lipid phosphatase proteins
    cd09101
    Location:392 → 695
    INPP5c_SHIP2-INPPL1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins
    PHA03247
    Location:867 → 1182
    PHA03247; large tegument protein UL36; Provisional
    cl15255
    Location:13 → 86
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein Strain
Heading Accession and Version

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