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SOAT1 sterol O-acyltransferase 1 [ Ovis aries (sheep) ]

Gene ID: 101121363, updated on 10-Oct-2024

Summary

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Gene symbol
SOAT1
Gene description
sterol O-acyltransferase 1
See related
EnsemblRapid:ENSOARG00020022293
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See SOAT1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 12 NC_056065.1 (60013175..60078646)

Chromosome 12 - NC_056065.1Genomic Context describing neighboring genes Neighboring gene torsin family 3 member A Neighboring gene ABL proto-oncogene 2, non-receptor tyrosine kinase Neighboring gene axonemal dynein light chain domain containing 1 Neighboring gene NPHS2 stomatin family member, podocin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056065.1 Chromosome 12 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cholesterol O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cholesterol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fatty-acyl-CoA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol efflux IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sterol O-acyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056065.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    60013175..60078646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_060396184.1 → XP_060252167.1  sterol O-acyltransferase 1 isoform X3

  2. XM_042229417.2 → XP_042085351.1  sterol O-acyltransferase 1 isoform X3

    UniProtKB/TrEMBL
    W5Q5C8
    Conserved Domains (1) summary
    pfam03062
    Location:270 → 532
    MBOAT; membrane-bound O-acyltransferase family

  3. XM_004013835.6 → XP_004013884.2  sterol O-acyltransferase 1 isoform X4

    See identical proteins and their annotated locations for XP_004013884.2

    UniProtKB/TrEMBL
    W5Q5C8
    Related
    ENSOARP00020028666.1, ENSOART00020034710.2
    Conserved Domains (1) summary
    pfam03062
    Location:252 → 514
    MBOAT; MBOAT, membrane-bound O-acyltransferase family

  4. XM_060396183.1 → XP_060252166.1  sterol O-acyltransferase 1 isoform X1

  5. XM_042229412.2 → XP_042085346.1  sterol O-acyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    W5Q5C8
    Conserved Domains (1) summary
    pfam03062
    Location:270 → 532
    MBOAT; membrane-bound O-acyltransferase family

  6. XM_042229413.2 → XP_042085347.1  sterol O-acyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    W5Q5C8
    Conserved Domains (1) summary
    pfam03062
    Location:252 → 514
    MBOAT; membrane-bound O-acyltransferase family
Nucleotide Protein Strain
Heading Accession and Version

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