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SFRP1 secreted frizzled related protein 1 [ Ovis aries (sheep) ]

Gene ID: 101121066, updated on 8-Mar-2024

Summary

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Gene symbol
SFRP1
Gene description
secreted frizzled related protein 1
See related
EnsemblRapid:ENSOARG00020024807
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See SFRP1 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 26 NC_056079.1 (35553993..35597129, complement)

Chromosome 26 - NC_056079.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA70 Neighboring gene small nuclear ribonucleoprotein Sm D2-like Neighboring gene uncharacterized LOC121818047 Neighboring gene uncharacterized LOC132658710

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056079.1 Chromosome 26 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
secreted frizzled-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056079.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    35553993..35597129 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027962478.2 → XP_027818279.1  secreted frizzled-related protein 1

    UniProtKB/TrEMBL
    A0A6P7DJT8, W5NWF6
    Related
    ENSOARP00020032177.1, ENSOART00020038837.2
    Conserved Domains (2) summary
    cd07443
    Location:46 → 169
    CRD_SFRP1; Cysteine-rich domain of the secreted frizzled-related protein 1 (SFRP1), a regulator of Wnt activity
    cd03580
    Location:177 → 300
    NTR_Sfrp1_like; NTR domain, Secreted frizzled-related protein (Sfrp) 1-like subfamily; composed of proteins similar to human Sfrp1, Sfrp2 and Sfrp5. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse ...
Nucleotide Protein Strain
Heading Accession and Version

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