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AKR1B1 aldo-keto reductase family 1 member B [ Ovis aries (sheep) ]

Gene ID: 101120824, updated on 11-Apr-2024

Summary

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Gene symbol
AKR1B1
Gene description
aldo-keto reductase family 1 member B
See related
EnsemblRapid:ENSOARG00020001166
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See AKR1B1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 4 NC_056057.1 (99789684..99806622, complement)

Chromosome 4 - NC_056057.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeats and guanylate kinase domain containing Neighboring gene selenide, water dikinase 2-like Neighboring gene solute carrier family 35 member B4 Neighboring gene aldo-keto reductase family 1 member B10 Neighboring gene bisphosphoglycerate mutase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056057.1 Chromosome 4 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of interferon-stimulated gene 15-kDa protein, cyclooxygenase (COX) 1, COX-2, aldo-keto reductase family 1, member B1, and prostaglandin E synthase in the spleen during early pregnancy in sheep. Yang L, et al. Anim Sci J, 2018 Nov. PMID 30191656

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. It is a interferon-stimulated gene.
    Title: Expression of interferon-stimulated gene 15-kDa protein, cyclooxygenase (COX) 1, COX-2, aldo-keto reductase family 1, member B1, and prostaglandin E synthase in the spleen during early pregnancy in sheep.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aldose reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
aldo-keto reductase family 1 member B1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056057.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    99789684..99806622 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004008077.4 → XP_004008126.1  aldo-keto reductase family 1 member B1 isoform X1

    See identical proteins and their annotated locations for XP_004008126.1

    UniProtKB/TrEMBL
    A0A6P3E936, W5PC00
    Related
    ENSOARP00020001445.2, ENSOART00020001735.2
    Conserved Domains (2) summary
    COG0656
    Location:1 → 297
    ARA1; Aldo/keto reductase, related to diketogulonate reductase [Secondary metabolites biosynthesis, transport and catabolism]
    COG0667
    Location:9 → 289
    Tas; Predicted oxidoreductase (related to aryl-alcohol dehydrogenase) [General function prediction only]

  2. XM_042248847.1 → XP_042104781.1  aldo-keto reductase family 1 member B1 isoform X2

    Conserved Domains (1) summary
    cl00470
    Location:1 → 172
    AKR_SF; Aldo-keto reductase (AKR) superfamily
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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