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NDST2 N-deacetylase and N-sulfotransferase 2 [ Ovis aries (sheep) ]

Gene ID: 101120545, updated on 10-Oct-2024

Summary

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Gene symbol
NDST2
Gene description
N-deacetylase and N-sulfotransferase 2
See related
EnsemblRapid:ENSOARG00020023160
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See NDST2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 25 NC_056078.1 (28914048..28922746, complement)

Chromosome 25 - NC_056078.1Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 1 Neighboring gene transfer RNA serine (anticodon GGA) Neighboring gene zinc finger SWIM-type containing 8 Neighboring gene calcium/calmodulin dependent protein kinase II gamma Neighboring gene uncharacterized LOC132658650

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056078.1 Chromosome 25 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables [heparan sulfate]-glucosamine N-sulfotransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2
Names
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056078.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    28914048..28922746 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_060406669.1 → XP_060262652.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X2

  2. XM_060406668.1 → XP_060262651.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P7DHF8
    Related
    ENSOARP00020029795.1, ENSOART00020036041.2

  3. XM_027962378.3 → XP_027818179.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X2

    UniProtKB/TrEMBL
    W5PEB5

  4. XM_027962375.3 → XP_027818176.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P7DHF8, W5PEB5
    Conserved Domains (2) summary
    pfam00685
    Location:603 → 852
    Sulfotransfer_1; Sulfotransferase domain
    pfam12062
    Location:25 → 514
    HSNSD; heparan sulfate-N-deacetylase

  5. XM_027962377.3 → XP_027818178.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P7DHF8, W5PEB5
    Conserved Domains (2) summary
    pfam00685
    Location:603 → 852
    Sulfotransfer_1; Sulfotransferase domain
    pfam12062
    Location:25 → 514
    HSNSD; heparan sulfate-N-deacetylase

  6. XM_060406671.1 → XP_060262654.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X4

    Related
    ENSOARP00020056714.1, ENSOART00020077241.1

  7. XM_060406670.1 → XP_060262653.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X3

    Related
    ENSOARP00020043733.1, ENSOART00020063189.1

  8. XM_060406672.1 → XP_060262655.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X5

Nucleotide Protein Strain
Heading Accession and Version

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