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HACD2 3-hydroxyacyl-CoA dehydratase 2 [ Ovis aries (sheep) ]

Gene ID: 101120135, updated on 8-Mar-2024

Summary

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Gene symbol
HACD2
Gene description
3-hydroxyacyl-CoA dehydratase 2
See related
EnsemblRapid:ENSOARG00020000118
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Also known as
PTPLB
Orthologs
human mouse all
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Genomic context

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See HACD2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 1 NC_056054.1 (188724639..188816775, complement)

Chromosome 1 - NC_056054.1Genomic Context describing neighboring genes Neighboring gene SEC22 homolog A, vesicle trafficking protein Neighboring gene adenylate cyclase 5 Neighboring gene serine/arginine repetitive matrix protein 1-like Neighboring gene myosin light chain kinase Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene coiled-coil domain containing 14

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056054.1 Chromosome 1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3-hydroxyacyl-CoA dehydratase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingolipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in very long-chain fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2
Names
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056054.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    188724639..188816775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027956481.3 → XP_027812282.1  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform X2

    UniProtKB/TrEMBL
    A0A6P7D1G5, W5QG36
    Related
    ENSOARP00020000081.1, ENSOART00020000139.2
    Conserved Domains (1) summary
    pfam04387
    Location:85 → 245
    PTPLA; Protein tyrosine phosphatase-like protein, PTPLA

  2. XM_042232294.2 → XP_042088228.1  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 isoform X1

    Related
    ENSOARP00020054654.1, ENSOART00020075219.1
    Conserved Domains (1) summary
    cl02156
    Location:37 → 282
    PTPLA; Protein tyrosine phosphatase-like protein, PTPLA
Nucleotide Protein Strain
Heading Accession and Version

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