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TNC tenascin C [ Ovis aries (sheep) ]

Gene ID: 101118337, updated on 10-Oct-2024

Summary

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Gene symbol
TNC
Gene description
tenascin C
See related
EnsemblRapid:ENSOARG00020005683
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See TNC in Genome Data Viewer
Location:
chromosome: 2
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (8661624..8762840)

Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene RNA N6-adenosine-methyltransferase METTL16-like Neighboring gene transfer RNA serine (anticodon GGA) Neighboring gene uncharacterized LOC121818580 Neighboring gene uncharacterized LOC132659278 Neighboring gene TNF superfamily member 8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tenascin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    8661624..8762840
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042242806.2 → XP_042098740.1  tenascin isoform X1

    UniProtKB/TrEMBL
    W5P7G4
    Conserved Domains (4) summary
    smart00060
    Location:1983 → 2059
    FN3; Fibronectin type 3 domain
    cd00063
    Location:2071 → 2157
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:2162 → 2371
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  2. XM_042242805.2 → XP_042098739.1  tenascin isoform X1

    UniProtKB/TrEMBL
    W5P7G4
    Related
    ENSOARP00020021423.2, ENSOART00020025833.2
    Conserved Domains (4) summary
    smart00060
    Location:1983 → 2059
    FN3; Fibronectin type 3 domain
    cd00063
    Location:2071 → 2157
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:2162 → 2371
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  3. XM_042242809.2 → XP_042098743.1  tenascin isoform X4

    UniProtKB/TrEMBL
    W5P7G4
    Conserved Domains (4) summary
    smart00060
    Location:1892 → 1968
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1980 → 2066
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:2071 → 2280
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  4. XM_042242811.2 → XP_042098745.1  tenascin isoform X6

    UniProtKB/TrEMBL
    W5P7G4
    Related
    ENSOARP00020022190.2, ENSOART00020026745.2
    Conserved Domains (4) summary
    smart00060
    Location:1891 → 1967
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1979 → 2065
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:2070 → 2279
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  5. XM_042242813.2 → XP_042098747.1  tenascin isoform X11

    UniProtKB/TrEMBL
    A0A836AII1
    Related
    ENSOARP00020021625.2, ENSOART00020026071.2
    Conserved Domains (4) summary
    smart00060
    Location:1800 → 1876
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1888 → 1974
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1979 → 2188
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  6. XM_042242807.2 → XP_042098741.1  tenascin isoform X2

    UniProtKB/TrEMBL
    W5P7G4
    Conserved Domains (4) summary
    smart00060
    Location:1982 → 2058
    FN3; Fibronectin type 3 domain
    cd00063
    Location:2070 → 2156
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:2161 → 2370
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  7. XM_060410803.1 → XP_060266786.1  tenascin isoform X7

  8. XM_060410807.1 → XP_060266790.1  tenascin isoform X13

  9. XM_042242808.2 → XP_042098742.1  tenascin isoform X3

    UniProtKB/TrEMBL
    W5P7G4
    Related
    ENSOARP00020021309.2, ENSOART00020025703.2
    Conserved Domains (4) summary
    smart00060
    Location:1892 → 1968
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1980 → 2066
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:2071 → 2280
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  10. XM_060410804.1 → XP_060266787.1  tenascin isoform X8

  11. XM_042242812.2 → XP_042098746.1  tenascin isoform X10

    UniProtKB/TrEMBL
    A0A836AII1
    Related
    ENSOARP00020021477.2, ENSOART00020025896.2
    Conserved Domains (4) summary
    smart00060
    Location:1800 → 1876
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1888 → 1974
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1979 → 2188
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  12. XM_042242815.2 → XP_042098749.1  tenascin isoform X14

    UniProtKB/TrEMBL
    A0A836AII1
    Related
    ENSOARP00020021371.2, ENSOART00020025772.2
    Conserved Domains (4) summary
    smart00060
    Location:1709 → 1785
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1797 → 1883
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1888 → 2097
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  13. XM_042242810.2 → XP_042098744.1  tenascin isoform X5

    UniProtKB/TrEMBL
    W5P7G4
    Conserved Domains (4) summary
    smart00060
    Location:1892 → 1968
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1980 → 2066
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:2071 → 2280
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  14. XM_060410805.1 → XP_060266788.1  tenascin isoform X9

  15. XM_060410806.1 → XP_060266789.1  tenascin isoform X12

  16. XM_042242814.2 → XP_042098748.1  tenascin isoform X15

    UniProtKB/TrEMBL
    A0A836AII1
    Conserved Domains (4) summary
    smart00060
    Location:1709 → 1785
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1797 → 1883
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1888 → 2097
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  17. XM_060410808.1 → XP_060266791.1  tenascin isoform X16

  18. XM_042242817.2 → XP_042098751.1  tenascin isoform X18

    UniProtKB/TrEMBL
    A0A836AII1
    Conserved Domains (4) summary
    smart00060
    Location:1345 → 1421
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1433 → 1519
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1524 → 1733
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  19. XM_042242816.2 → XP_042098750.1  tenascin isoform X17

    UniProtKB/TrEMBL
    W5P7G4
    Conserved Domains (4) summary
    smart00060
    Location:1528 → 1604
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1616 → 1702
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1707 → 1916
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain

  20. XM_042242818.2 → XP_042098752.1  tenascin isoform X19

    Conserved Domains (4) summary
    smart00060
    Location:1254 → 1330
    FN3; Fibronectin type 3 domain
    cd00063
    Location:1342 → 1428
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00087
    Location:1433 → 1642
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam18720
    Location:190 → 217
    EGF_Tenascin; Tenascin EGF domain
Nucleotide Protein Strain
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