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CERS5 ceramide synthase 5 [ Ovis aries (sheep) ]

Gene ID: 101117661, updated on 10-Oct-2024

Summary

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Gene symbol
CERS5
Gene description
ceramide synthase 5
See related
EnsemblRapid:ENSOARG00020023406
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See CERS5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (136155618..136185990)

Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene La ribonucleoprotein 4 Neighboring gene family with sequence similarity 186 member A Neighboring gene LIM domain and actin binding 1 Neighboring gene cytochrome c oxidase assembly protein COX14 Neighboring gene glycerol-3-phosphate dehydrogenase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sphingosine N-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ceramide synthase 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    136155618..136185990
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027967342.2 → XP_027823143.1  ceramide synthase 5 isoform X2

    UniProtKB/TrEMBL
    W5Q924
    Related
    ENSOARP00020062077.1, ENSOART00020079603.1

  2. XM_027967341.2 → XP_027823142.1  ceramide synthase 5 isoform X1

    UniProtKB/TrEMBL
    A0A6P7DWE5, W5P6K0
    Related
    ENSOARP00020030154.2, ENSOART00020036469.2
    Conserved Domains (2) summary
    smart00724
    Location:139 → 339
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:89 → 136
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  3. XM_042246746.2 → XP_042102680.1  ceramide synthase 5 isoform X3

    UniProtKB/TrEMBL
    W5Q923
    Conserved Domains (2) summary
    smart00724
    Location:86 → 286
    TLC; TRAM, LAG1 and CLN8 homology domains
    cd00086
    Location:36 → 83
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

  4. XM_060412618.1 → XP_060268601.1  ceramide synthase 5 isoform X4

  5. XM_060412619.1 → XP_060268602.1  ceramide synthase 5 isoform X5

Nucleotide Protein Strain
Heading Accession and Version

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