U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [ Ovis aries (sheep) ]

Gene ID: 101117348, updated on 10-Oct-2024

Summary

Go to the top of the page Help
Gene symbol
PIK3CD
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
See related
EnsemblRapid:ENSOARG00020017935
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PIK3CD in Genome Data Viewer
Location:
chromosome: 12
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 12 NC_056065.1 (43042392..43103621, complement)

Chromosome 12 - NC_056065.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132657513 Neighboring gene calsyntenin 1 Neighboring gene U6 spliceosomal RNA Neighboring gene transmembrane protein 201

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_056065.1 Chromosome 12 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056065.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    43042392..43103621 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042257285.1 → XP_042113219.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X2

    UniProtKB/TrEMBL
    A0A836D0Q9
    Related
    ENSOARP00020022906.2, ENSOART00020027618.2
    Conserved Domains (5) summary
    cd08693
    Location:314 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:505 → 683
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:675 → 1041
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    cl02483
    Location:31 → 108
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl02484
    Location:183 → 281
    PI3K_rbd; PI3-kinase family, ras-binding domain

  2. XM_027975658.2 → XP_027831459.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X3

    UniProtKB/TrEMBL
    A0A836D0Q9
    Related
    ENSOARP00020060303.1, ENSOART00020068267.1

  3. XM_042257276.1 → XP_042113210.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    A0A836D0Q9
    Conserved Domains (5) summary
    cd08693
    Location:314 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:504 → 684
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:676 → 1042
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:178 → 281
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

  4. XM_042257280.1 → XP_042113214.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    A0A836D0Q9
    Conserved Domains (5) summary
    cd08693
    Location:314 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:504 → 684
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:676 → 1042
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:178 → 281
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

  5. XM_060396507.1 → XP_060252490.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

  6. XM_060396504.1 → XP_060252487.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

  7. XM_060396506.1 → XP_060252489.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

  8. XM_060396505.1 → XP_060252488.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

  9. XM_042257281.1 → XP_042113215.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    A0A836D0Q9
    Conserved Domains (5) summary
    cd08693
    Location:314 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:504 → 684
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:676 → 1042
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:178 → 281
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

  10. XM_060396508.1 → XP_060252491.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.