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CD44 CD44 molecule (IN blood group) [ Ovis aries (sheep) ]

Gene ID: 101113884, updated on 10-Oct-2024

Summary

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Gene symbol
CD44
Gene description
CD44 molecule (IN blood group)
See related
EnsemblRapid:ENSOARG00020013570
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See CD44 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 15 NC_056068.1 (64457783..64547194)

Chromosome 15 - NC_056068.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene uncharacterized LOC132657832 Neighboring gene solute carrier family 1 member 2 Neighboring gene uncharacterized LOC132657833

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056068.1 Chromosome 15 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of the hyaluronan system in ovine endometrium by ovarian steroids. Raheem KA, et al. Reproduction, 2013 May. PMID 23630333
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of macrophage migration inhibitory factor receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CD44 antigen
Names
CD44 molecule (Indian blood group)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056068.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    64457783..64547194
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027979619.3 → XP_027835420.2  CD44 antigen isoform X1

    UniProtKB/TrEMBL
    W5QBV7
    Related
    ENSOARP00020050201.1, ENSOART00020020729.2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  2. XM_027979621.3 → XP_027835422.2  CD44 antigen isoform X4

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  3. XM_042233348.2 → XP_042089282.1  CD44 antigen isoform X10

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  4. XM_042233343.2 → XP_042089277.1  CD44 antigen isoform X7

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  5. XM_042233342.2 → XP_042089276.1  CD44 antigen isoform X5

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  6. XM_042233349.2 → XP_042089283.1  CD44 antigen isoform X12

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  7. XM_042233351.2 → XP_042089285.1  CD44 antigen isoform X17

    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  8. XM_042233345.2 → XP_042089279.1  CD44 antigen isoform X9

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  9. XM_060399517.1 → XP_060255500.1  CD44 antigen isoform X13

  10. XM_042233350.2 → XP_042089284.1  CD44 antigen isoform X15

    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  11. XM_042233352.2 → XP_042089286.1  CD44 antigen isoform X19

    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  12. XM_042233344.2 → XP_042089278.1  CD44 antigen isoform X8

    UniProtKB/TrEMBL
    W5QBV7
    Related
    ENSOARP00020060899.1, ENSOART00020021260.2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  13. XM_027979626.3 → XP_027835427.1  CD44 antigen isoform X20

  14. XM_042233354.2 → XP_042089288.1  CD44 antigen isoform X24

    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  15. XM_027979620.3 → XP_027835421.2  CD44 antigen isoform X2

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  16. XM_042233341.2 → XP_042089275.1  CD44 antigen isoform X3

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  17. XM_042233347.2 → XP_042089281.1  CD44 antigen isoform X11

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  18. XM_060399518.1 → XP_060255501.1  CD44 antigen isoform X22

  19. XM_027979622.3 → XP_027835423.2  CD44 antigen isoform X6

    UniProtKB/TrEMBL
    W5QBV7
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  20. XM_027979623.3 → XP_027835424.2  CD44 antigen isoform X14

    UniProtKB/TrEMBL
    W5QBV7
    Related
    ENSOARP00020044180.1, ENSOART00020021319.2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  21. XM_027979624.3 → XP_027835425.2  CD44 antigen isoform X16

    Related
    ENSOARP00020037830.1, ENSOART00020021193.2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  22. XM_027979625.3 → XP_027835426.2  CD44 antigen isoform X18

    Related
    ENSOARP00020036473.1, ENSOART00020021289.2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  23. XM_042233353.2 → XP_042089287.1  CD44 antigen isoform X21

    Related
    ENSOARP00020057577.1, ENSOART00020020780.2
    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  24. XM_042233355.2 → XP_042089289.1  CD44 antigen isoform X25

    Conserved Domains (1) summary
    cd03516
    Location:26 → 168
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

  25. XM_027979627.3 → XP_027835428.1  CD44 antigen isoform X23

    Related
    ENSOARP00020063162.1, ENSOART00020020836.2

  26. XM_027979628.3 → XP_027835429.1  CD44 antigen isoform X26

    Related
    ENSOARP00020058550.1, ENSOART00020021233.2

  27. XM_027979629.3 → XP_027835430.1  CD44 antigen isoform X27

    Related
    ENSOARP00020049421.1, ENSOART00020020808.2
Nucleotide Protein Strain
Heading Accession and Version

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