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LPIN3 lipin 3 [ Ovis aries (sheep) ]

Gene ID: 101106450, updated on 6-Jun-2024

Summary

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Gene symbol
LPIN3
Gene description
lipin 3
See related
EnsemblRapid:ENSOARG00020014085
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See LPIN3 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 13 NC_056066.1 (69954668..69973231)

Chromosome 13 - NC_056066.1Genomic Context describing neighboring genes Neighboring gene zinc fingers and homeoboxes 3 Neighboring gene receptor-binding cancer antigen expressed on SiSo cells-like Neighboring gene elastin microfibril interfacer 3 Neighboring gene chromodomain helicase DNA binding protein 6 Neighboring gene uncharacterized LOC121816276

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056066.1 Chromosome 13 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidate phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fatty acid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triglyceride biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidate phosphatase LPIN3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056066.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    69954668..69973231
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027977198.3 → XP_027832999.1  phosphatidate phosphatase LPIN3 isoform X1

    UniProtKB/TrEMBL
    A0A835ZW59
    Conserved Domains (4) summary
    PHA03307
    Location:93 → 451
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:592 → 817
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam16876
    Location:438 → 529
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  2. XM_060397038.1 → XP_060253021.1  phosphatidate phosphatase LPIN3 isoform X2

    UniProtKB/TrEMBL
    A0A835ZW59

  3. XM_042230140.2 → XP_042086074.1  phosphatidate phosphatase LPIN3 isoform X2

    UniProtKB/TrEMBL
    A0A835ZW59
    Conserved Domains (4) summary
    PHA03307
    Location:93 → 450
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:591 → 816
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam16876
    Location:437 → 528
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  4. XM_042230138.2 → XP_042086072.1  phosphatidate phosphatase LPIN3 isoform X1

    UniProtKB/TrEMBL
    A0A835ZW59
    Related
    ENSOARP00020017829.1, ENSOART00020021532.2
    Conserved Domains (4) summary
    PHA03307
    Location:93 → 451
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:592 → 817
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam16876
    Location:438 → 529
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  5. XM_060397037.1 → XP_060253020.1  phosphatidate phosphatase LPIN3 isoform X2

    UniProtKB/TrEMBL
    A0A835ZW59

  6. XM_015099885.4 → XP_014955371.2  phosphatidate phosphatase LPIN3 isoform X1

    UniProtKB/TrEMBL
    A0A835ZW59
    Conserved Domains (4) summary
    PHA03307
    Location:93 → 451
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:592 → 817
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam16876
    Location:438 → 529
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  7. XM_042230141.2 → XP_042086075.1  phosphatidate phosphatase LPIN3 isoform X3

    UniProtKB/TrEMBL
    A0A835ZW59
    Conserved Domains (3) summary
    smart00775
    Location:638 → 794
    LNS2; This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins
    PHA03307
    Location:93 → 449
    PHA03307; transcriptional regulator ICP4; Provisional
    COG5083
    Location:1 → 137
    SMP2; Phosphatidate phosphatase PAH1, contains Lipin and LNS2 domains. can be involved in plasmid maintenance [Lipid transport and metabolism]

  8. XM_027977200.3 → XP_027833001.1  phosphatidate phosphatase LPIN3 isoform X2

    UniProtKB/TrEMBL
    A0A835ZW59
    Conserved Domains (4) summary
    PHA03307
    Location:93 → 450
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:591 → 816
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam16876
    Location:437 → 528
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  9. XM_060397040.1 → XP_060253023.1  phosphatidate phosphatase LPIN3 isoform X4

    UniProtKB/TrEMBL
    A0A835ZW59

  10. XM_027977199.3 → XP_027833000.1  phosphatidate phosphatase LPIN3 isoform X1

    UniProtKB/TrEMBL
    A0A835ZW59
    Conserved Domains (4) summary
    PHA03307
    Location:93 → 451
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam04571
    Location:1 → 107
    Lipin_N; lipin, N-terminal conserved region
    pfam08235
    Location:592 → 817
    LNS2; LNS2 (Lipin/Ned1/Smp2)
    pfam16876
    Location:438 → 529
    Lipin_mid; Lipin/Ned1/Smp2 multi-domain protein middle domain

  11. XM_060397039.1 → XP_060253022.1  phosphatidate phosphatase LPIN3 isoform X2

    UniProtKB/TrEMBL
    A0A835ZW59
Nucleotide Protein Strain
Heading Accession and Version

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