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SPTLC1 serine palmitoyltransferase long chain base subunit 1 [ Ovis aries (sheep) ]

Gene ID: 101105721, updated on 10-Oct-2024

Summary

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Gene symbol
SPTLC1
Gene description
serine palmitoyltransferase long chain base subunit 1
See related
EnsemblRapid:ENSOARG00020000576
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See SPTLC1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (27062495..27127800, complement)

Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene transfer RNA serine (anticodon GGA) Neighboring gene receptor tyrosine kinase like orphan receptor 2 Neighboring gene serine/threonine-protein kinase MRCK alpha-like Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine C-palmitoyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine palmitoyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    27062495..27127800 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004004066.5 → XP_004004115.1  serine palmitoyltransferase 1 isoform X2

    See identical proteins and their annotated locations for XP_004004115.1

    UniProtKB/TrEMBL
    A0A6P3E0Y3, W5PDE3
    Related
    ENSOARP00020062579.1, ENSOART00020069616.1
    Conserved Domains (1) summary
    cl18945
    Location:11 → 472
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

  2. XM_060410820.1 → XP_060266803.1  serine palmitoyltransferase 1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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