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PLCB1 phospholipase C beta 1 [ Ovis aries (sheep) ]

Gene ID: 101103585, updated on 10-Oct-2024

Summary

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Gene symbol
PLCB1
Gene description
phospholipase C beta 1
See related
EnsemblRapid:ENSOARG00020023836
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See PLCB1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 13 NC_056066.1 (747720..1604993)

Chromosome 13 - NC_056066.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121816288 Neighboring gene thioredoxin related transmembrane protein 4 Neighboring gene uncharacterized LOC132657599 Neighboring gene M-phase phosphoprotein 6-like Neighboring gene phospholipase C beta 4 Neighboring gene lysosomal associated membrane protein family member 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056066.1 Chromosome 13 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in memory IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
Names
phospholipase C, beta 1 (phosphoinositide-specific)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056066.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    747720..1604993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042230393.1 → XP_042086327.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1

    UniProtKB/TrEMBL
    A0A835ZTL4
    Related
    ENSOARP00020031062.2, ENSOART00020037517.2
    Conserved Domains (6) summary
    TIGR01069
    Location:1086 → 1178
    mutS2; MutS2 family protein
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PRK12727
    Location:835 → 943
    PRK12727; flagellar biosynthesis protein FlhF
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)

  2. XM_060397115.1 → XP_060253098.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2

    Related
    ENSOARP00020047130.1, ENSOART00020078612.1
Nucleotide Protein Strain
Heading Accession and Version

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