U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase [ Felis catus (domestic cat) ]

Gene ID: 101099569, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
HMGCL
Official Full Name
3-hydroxy-3-methylglutaryl-CoA lyase
Primary source
VGNC:VGNC:67595
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See HMGCL in Genome Data Viewer
Location:
chromosome: C1
Exon count:
9
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) C1 NC_058375.1 (17664469..17681741, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) C1 NC_018730.3 (17748939..17767307, complement)

Chromosome C1 - NC_058375.1Genomic Context describing neighboring genes Neighboring gene PITH domain containing 1 Neighboring gene lysophospholipase 2 Neighboring gene UDP-galactose-4-epimerase Neighboring gene U4 spliceosomal RNA Neighboring gene alpha-L-fucosidase 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
hydroxymethylglutaryl-CoA lyase, mitochondrial
Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058375.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    17664469..17681741 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003989655.6 → XP_003989704.1  hydroxymethylglutaryl-CoA lyase, mitochondrial

    UniProtKB/TrEMBL
    M3WFT8
    Conserved Domains (2) summary
    cd07938
    Location:35 → 308
    DRE_TIM_HMGL; 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain
    pfam00682
    Location:32 → 306
    HMGL-like; HMGL-like
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.