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MCOLN1 mucolipin TRP cation channel 1 [ Felis catus (domestic cat) ]

Gene ID: 101097951, updated on 17-Aug-2024

Summary

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Official Symbol
MCOLN1
Official Full Name
mucolipin TRP cation channel 1
Primary source
VGNC:VGNC:63418
See related
EnsemblRapid:ENSFCTG00005030845
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See MCOLN1 in Genome Data Viewer
Location:
chromosome: A2
Exon count:
15
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) A2 NC_058369.1 (6219187..6227756, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) A2 NC_018724.3 (6250623..6259163, complement)

Chromosome A2 - NC_058369.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109497746 Neighboring gene patatin like phospholipase domain containing 6 Neighboring gene uncharacterized LOC105261148 Neighboring gene zinc finger protein 358 Neighboring gene uncharacterized LOC123384109 Neighboring gene stabilizer of axonemal microtubules 5 Neighboring gene peroxisomal biogenesis factor 11 gamma

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAADP-sensitive calcium-release channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mucolipin-1
Names
mucolipin 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058369.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    6219187..6227756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045053111.1 → XP_044909046.1  mucolipin-1 isoform X4

  2. XM_003981811.6 → XP_003981860.1  mucolipin-1 isoform X3

    UniProtKB/TrEMBL
    A0A5F5XTH4, M3W9B1
    Related
    ENSFCTP00005058411.1, ENSFCTT00005085883.1
    Conserved Domains (2) summary
    pfam08016
    Location:385 → 521
    PKD_channel; Polycystin cation channel
    cd21070
    Location:109 → 289
    ELD_TRPML1; extracytosolic/lumenal domain (ELD) found in transient receptor potential channel mucolipin 1 (TRPML1)

  3. XM_006928355.5 → XP_006928417.4  mucolipin-1 isoform X1

    UniProtKB/TrEMBL
    A0A5F5XTH4
    Conserved Domains (1) summary
    PLN03223
    Location:373 → 579
    PLN03223; Polycystin cation channel protein; Provisional

  4. XM_006928356.5 → XP_006928418.4  mucolipin-1 isoform X2

    UniProtKB/TrEMBL
    A0A5F5XTH4
    Conserved Domains (1) summary
    PLN03223
    Location:371 → 577
    PLN03223; Polycystin cation channel protein; Provisional
Nucleotide Protein
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