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ACVRL1 activin A receptor like type 1 [ Felis catus (domestic cat) ]

Gene ID: 101097406, updated on 17-Aug-2024

Summary

Official Symbol
ACVRL1
Official Full Name
activin A receptor like type 1
Primary source
VGNC:VGNC:59567
See related
EnsemblRapid:ENSFCTG00005016694
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Also known as
HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
Orthologs
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Genomic context

See ACVRL1 in Genome Data Viewer
Location:
chromosome: B4
Exon count:
14
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) B4 NC_058374.1 (78380158..78396652)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) B4 NC_018729.3 (80485179..80500881)

Chromosome B4 - NC_058374.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 33 Neighboring gene uncharacterized LOC109501578 Neighboring gene uncharacterized LOC109501580 Neighboring gene activin A receptor type 1B

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables transforming growth factor beta receptor activity, type I IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in dorsal/ventral pattern formation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of BMP receptor complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
serine/threonine-protein kinase receptor R3
Names
activin A receptor type II-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058374.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    78380158..78396652
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045061830.1XP_044917765.1  serine/threonine-protein kinase receptor R3 isoform X1

    UniProtKB/TrEMBL
    M3VUE2
    Conserved Domains (2) summary
    cd14142
    Location:198495
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:175202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
  2. XM_023257089.2XP_023112857.1  serine/threonine-protein kinase receptor R3 isoform X2

    Related
    ENSFCTP00005034669.1, ENSFCTT00005048052.1
    Conserved Domains (3) summary
    pfam08515
    Location:175202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
    cl17812
    Location:382452
    Phage_base_V; Type VI secretion system, phage-baseplate injector
    cl21453
    Location:198355
    PKc_like; Protein Kinases, catalytic domain
  3. XM_011283947.3XP_011282249.1  serine/threonine-protein kinase receptor R3 isoform X1

    See identical proteins and their annotated locations for XP_011282249.1

    UniProtKB/TrEMBL
    M3VUE2
    Related
    ENSFCTP00005034806.1, ENSFCTT00005048205.1
    Conserved Domains (2) summary
    cd14142
    Location:198495
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:175202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
  4. XM_045061832.1XP_044917767.1  serine/threonine-protein kinase receptor R3 isoform X1

    UniProtKB/TrEMBL
    M3VUE2
    Conserved Domains (2) summary
    cd14142
    Location:198495
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:175202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
  5. XM_045061831.1XP_044917766.1  serine/threonine-protein kinase receptor R3 isoform X1

    UniProtKB/TrEMBL
    M3VUE2
    Conserved Domains (2) summary
    cd14142
    Location:198495
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam08515
    Location:175202
    TGF_beta_GS; Transforming growth factor beta type I GS-motif