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THBS3 thrombospondin 3 [ Felis catus (domestic cat) ]

Gene ID: 101093580, updated on 17-Aug-2024

Summary

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Official Symbol
THBS3
Official Full Name
thrombospondin 3
Primary source
VGNC:VGNC:66156
See related
EnsemblRapid:ENSFCTG00005008552
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See THBS3 in Genome Data Viewer
Location:
chromosome: F1
Exon count:
25
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) F1 NC_058384.1 (67934880..67944923)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) F1 NC_018739.3 (70369527..70379493)

Chromosome F1 - NC_058384.1Genomic Context describing neighboring genes Neighboring gene endosomal transmembrane epsin interactor 3 Neighboring gene glucosylceramidase beta 1 Neighboring gene metaxin 1 Neighboring gene mucin 1, cell surface associated Neighboring gene tripartite motif containing 46

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thrombospondin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058384.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    67934880..67944923
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023247381.2 → XP_023103149.2  thrombospondin-3 isoform X1

    UniProtKB/TrEMBL
    M3W658
    Related
    ENSFCTP00005015673.1, ENSFCTT00005024027.1
    Conserved Domains (8) summary
    cd00054
    Location:316 → 352
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:528 → 550
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:551 → 586
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:458 → 491
    TSP3_1C; TSP3 repeat_1C [structural motif]
    cd16079
    Location:227 → 269
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    pfam02412
    Location:551 → 586
    TSP_3; Thrombospondin type 3 repeat
    NF000535
    Location:449 → 652
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    cl22861
    Location:23 → 193
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

  2. XM_045048754.1 → XP_044904689.1  thrombospondin-3 isoform X4

    UniProtKB/TrEMBL
    M3W658
    Conserved Domains (6) summary
    cd00054
    Location:316 → 352
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:528 → 550
    TSP3; TSP3 repeat_short [structural motif]
    sd00003
    Location:458 → 491
    TSP3_1C; TSP3 repeat_1C [structural motif]
    cd16079
    Location:227 → 269
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    pfam02412
    Location:647 → 681
    TSP_3; Thrombospondin type 3 repeat
    cl22861
    Location:23 → 193
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

  3. XM_045048753.1 → XP_044904688.1  thrombospondin-3 isoform X3

    UniProtKB/TrEMBL
    M3W658
    Conserved Domains (8) summary
    cd00054
    Location:290 → 326
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:502 → 524
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:525 → 560
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:432 → 465
    TSP3_1C; TSP3 repeat_1C [structural motif]
    cd16079
    Location:201 → 243
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    pfam02412
    Location:525 → 560
    TSP_3; Thrombospondin type 3 repeat
    NF000535
    Location:423 → 626
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    cl22861
    Location:1 → 167
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

  4. XM_045048752.1 → XP_044904687.1  thrombospondin-3 isoform X2

    UniProtKB/TrEMBL
    M3W658
    Conserved Domains (8) summary
    cd00054
    Location:304 → 340
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:516 → 538
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:539 → 574
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:446 → 479
    TSP3_1C; TSP3 repeat_1C [structural motif]
    cd16079
    Location:215 → 257
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    pfam02412
    Location:539 → 574
    TSP_3; Thrombospondin type 3 repeat
    NF000535
    Location:437 → 640
    MSCRAMM_SdrC; MSCRAMM family adhesin SdrC
    cl22861
    Location:14 → 181
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
Nucleotide Protein
Heading Accession and Version

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