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NCSTN nicastrin [ Felis catus (domestic cat) ]

Gene ID: 101090586, updated on 8-Mar-2024

Summary

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Official Symbol
NCSTN
Official Full Name
nicastrin
Primary source
VGNC:VGNC:63745
See related
EnsemblRapid:ENSFCTG00005007760
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See NCSTN in Genome Data Viewer
Location:
chromosome: F1
Exon count:
17
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) F1 NC_058384.1 (64268312..64283190, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) F1 NC_018739.3 (66641842..66656725, complement)

Chromosome F1 - NC_058384.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109495796 Neighboring gene nescient helix-loop-helix 1 Neighboring gene COPI coat complex subunit alpha Neighboring gene peroxisomal biogenesis factor 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nicastrin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058384.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    64268312..64283190 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011291113.4 → XP_011289415.2  nicastrin

    UniProtKB/TrEMBL
    A0A337S9P8
    Related
    ENSFCTP00005014194.1, ENSFCTT00005021664.1
    Conserved Domains (1) summary
    cd03881
    Location:52 → 654
    M28_Nicastrin; M28 Zn-peptidase nicastrin, a main component of gamma-secretase complex
Nucleotide Protein
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