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EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 [ Felis catus (domestic cat) ]

Gene ID: 101087192, updated on 17-Aug-2024

Summary

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Official Symbol
EDEM3
Official Full Name
ER degradation enhancing alpha-mannosidase like protein 3
Primary source
VGNC:VGNC:61724
See related
EnsemblRapid:ENSFCTG00005005869
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See EDEM3 in Genome Data Viewer
Location:
chromosome: F1
Exon count:
22
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) F1 NC_058384.1 (23480519..23560710)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) F1 NC_018739.3 (25653695..25735142)

Chromosome F1 - NC_058384.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene niban apoptosis regulator 1 Neighboring gene uncharacterized LOC111558386 Neighboring gene serine/threonine-protein kinase PLK1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endoplasmic reticulum mannose trimming IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mannose trimming involved in glycoprotein ERAD pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ER degradation-enhancing alpha-mannosidase-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058384.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    23480519..23560710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019821730.3 → XP_019677289.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X1

    UniProtKB/TrEMBL
    M3W7T1
    Conserved Domains (3) summary
    cd02126
    Location:666 → 791
    PA_EDEM3_like; protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar to Class I ...
    pfam01532
    Location:60 → 499
    Glyco_hydro_47; Glycosyl hydrolase family 47
    pfam07263
    Location:819 → 918
    DMP1; Dentin matrix protein 1 (DMP1)

  2. XM_019821731.3 → XP_019677290.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X3

    UniProtKB/TrEMBL
    M3W7T1
    Conserved Domains (3) summary
    cd02126
    Location:666 → 791
    PA_EDEM3_like; protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar to Class I ...
    pfam01532
    Location:60 → 499
    Glyco_hydro_47; Glycosyl hydrolase family 47
    pfam07263
    Location:818 → 917
    DMP1; Dentin matrix protein 1 (DMP1)

  3. XM_019821732.3 → XP_019677291.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X6

    UniProtKB/TrEMBL
    M3W7T1
    Conserved Domains (3) summary
    cd02126
    Location:647 → 772
    PA_EDEM3_like; protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar to Class I ...
    pfam01532
    Location:60 → 499
    Glyco_hydro_47; Glycosyl hydrolase family 47
    pfam07263
    Location:800 → 899
    DMP1; Dentin matrix protein 1 (DMP1)

  4. XM_019821734.3 → XP_019677293.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X8

    UniProtKB/TrEMBL
    M3W7T1
    Conserved Domains (3) summary
    cd02126
    Location:647 → 772
    PA_EDEM3_like; protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar to Class I ...
    pfam01532
    Location:60 → 499
    Glyco_hydro_47; Glycosyl hydrolase family 47
    pfam07263
    Location:766 → 883
    DMP1; Dentin matrix protein 1 (DMP1)

  5. XM_019821733.3 → XP_019677292.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X7

    UniProtKB/TrEMBL
    M3W7T1
    Conserved Domains (3) summary
    cd02126
    Location:646 → 771
    PA_EDEM3_like; protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar to Class I ...
    pfam01532
    Location:60 → 499
    Glyco_hydro_47; Glycosyl hydrolase family 47
    pfam07263
    Location:799 → 898
    DMP1; Dentin matrix protein 1 (DMP1)

  6. XM_019821735.3 → XP_019677294.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X10

    UniProtKB/TrEMBL
    A0A5F5Y2R4
    Conserved Domains (2) summary
    cd02126
    Location:666 → 791
    PA_EDEM3_like; PA_EDEM3_like: protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar ...
    pfam01532
    Location:60 → 499
    Glyco_hydro_47; Glycosyl hydrolase family 47

  7. XM_011291003.4 → XP_011289305.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X4

    UniProtKB/TrEMBL
    M3W7T1
    Related
    ENSFCTP00005011299.1, ENSFCTT00005016485.1
    Conserved Domains (2) summary
    cd02126
    Location:666 → 791
    PA_EDEM3_like; PA_EDEM3_like: protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar ...
    pfam01532
    Location:60 → 499
    Glyco_hydro_47; Glycosyl hydrolase family 47

  8. XM_011291002.4 → XP_011289304.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A2I2UR70, M3W7T1
    Related
    ENSFCTP00005011277.1, ENSFCTT00005016457.1
    Conserved Domains (2) summary
    cd02126
    Location:665 → 790
    PA_EDEM3_like; PA_EDEM3_like: protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar ...
    pfam01532
    Location:60 → 499
    Glyco_hydro_47; Glycosyl hydrolase family 47

  9. XM_011291004.4 → XP_011289306.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X5

    UniProtKB/TrEMBL
    A0A337RZR6, M3W7T1
    Related
    ENSFCTP00005011251.1, ENSFCTT00005016430.1
    Conserved Domains (2) summary
    cd02126
    Location:665 → 790
    PA_EDEM3_like; PA_EDEM3_like: protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar ...
    pfam01532
    Location:60 → 499
    Glyco_hydro_47; Glycosyl hydrolase family 47

  10. XM_023247241.2 → XP_023103009.1  ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X9

    UniProtKB/TrEMBL
    M3W7T1
    Conserved Domains (3) summary
    cd02126
    Location:588 → 713
    PA_EDEM3_like; protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar to Class I ...
    pfam01532
    Location:1 → 421
    Glyco_hydro_47; Glycosyl hydrolase family 47
    pfam07263
    Location:741 → 840
    DMP1; Dentin matrix protein 1 (DMP1)
Nucleotide Protein
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