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NAE1 NEDD8 activating enzyme E1 subunit 1 [ Felis catus (domestic cat) ]

Gene ID: 101086523, updated on 17-Aug-2024

Summary

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Official Symbol
NAE1
Official Full Name
NEDD8 activating enzyme E1 subunit 1
Primary source
VGNC:VGNC:67883
See related
EnsemblRapid:ENSFCTG00005003175
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See NAE1 in Genome Data Viewer
Location:
chromosome: E2
Exon count:
23
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) E2 NC_058382.1 (42449800..42506649, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) E2 NC_018737.3 (44638389..44670532, complement)

Chromosome E2 - NC_058382.1Genomic Context describing neighboring genes Neighboring gene dynein cytoplasmic 1 light intermediate chain 2 Neighboring gene telomere repeat binding bouquet formation protein 1 Neighboring gene carbonic anhydrase 7 Neighboring gene pyruvate dehydrogenase phosphatase catalytic subunit 2 Neighboring gene cadherin 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NEDD8 activating enzyme activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin activating enzyme activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein neddylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NEDD8-activating enzyme E1 regulatory subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058382.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    42449800..42506649 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045047102.1 → XP_044903037.1  NEDD8-activating enzyme E1 regulatory subunit isoform X2

    UniProtKB/TrEMBL
    A0A337SK43
    Related
    ENSFCTP00005005250.1, ENSFCTT00005008475.1
    Conserved Domains (2) summary
    cd01493
    Location:1 → 443
    APPBP1_RUB; Ubiquitin activating enzyme (E1) subunit APPBP1. APPBP1 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
    TIGR01408
    Location:321 → 424
    Ube1; ubiquitin-activating enzyme E1

  2. XM_011290125.3 → XP_011288427.1  NEDD8-activating enzyme E1 regulatory subunit isoform X1

    UniProtKB/TrEMBL
    A0A337SK43
    Related
    ENSFCTP00005005244.1, ENSFCTT00005008464.1
    Conserved Domains (1) summary
    cd01493
    Location:11 → 532
    APPBP1_RUB; Ubiquitin activating enzyme (E1) subunit APPBP1. APPBP1 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
Nucleotide Protein
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