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Lipo2 lipase, member O2 [ Mus musculus (house mouse) ]

Gene ID: 101055671, updated on 17-Aug-2024

Summary

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Official Symbol
Lipo2provided by MGI
Official Full Name
lipase, member O2provided by MGI
Primary source
MGI:MGI:3644466
See related
Ensembl:ENSMUSG00000087303 AllianceGenome:MGI:3644466
Gene type
protein coding
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm8981; EG668114
Summary
Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 1.8), ovary adult (RPKM 1.6) and 28 other tissues See more
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Genomic context

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Location:
19 C1; 19 29.23 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (33697067..33739461, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (33719670..33762022, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 18293 Neighboring gene predicted gene 8980 Neighboring gene STARR-seq mESC enhancer starr_45979 Neighboring gene STARR-seq mESC enhancer starr_45980 Neighboring gene STARR-seq mESC enhancer starr_45981 Neighboring gene STARR-seq mESC enhancer starr_45982 Neighboring gene lipase, member O1 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 15 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Comparative studies of mammalian acid lipases: Evidence for a new gene family in mouse and rat (Lipo). Holmes RS, et al. Comp Biochem Physiol Part D Genomics Proteomics, 2010 Sep. PMID 20598663, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables sterol esterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in sterol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
lipase, member O2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001322338.1 → NP_001309267.1  lipase, member O2 precursor

    Status: INFERRED

    Source sequence(s)
    AC122846
    Consensus CDS
    CCDS84434.1
    UniProtKB/TrEMBL
    D3YY49, Q3TD80
    Related
    ENSMUSP00000118907.2, ENSMUST00000147153.4
    Conserved Domains (1) summary
    PLN02872
    Location:34 → 391
    PLN02872; triacylglycerol lipase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    33697067..33739461 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161367.1 → XP_036017260.1  lipase, member O2 isoform X1

    UniProtKB/TrEMBL
    D3YY49, Q3TD80
    Conserved Domains (1) summary
    PLN02872
    Location:34 → 391
    PLN02872; triacylglycerol lipase
Nucleotide Protein
Heading Accession and Version

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